Luthra Karuna, Gauthaman Dinesh Kumar, Lele Vikram
Department of Nuclear Medicine and PET-CT, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
Indian J Nucl Med. 2022 Jan-Mar;37(1):83-90. doi: 10.4103/ijnm.ijnm_101_21. Epub 2022 Mar 25.
Tumor-induced osteomalacia (TIO) is a rare cause of severe debilitating osteomalacia, due to hypophosphatemia. A strong clinical suspicion based on biochemical parameters can lead to the search for a culprit tumor in the body. The disease entity is more commonly caused by benign mesenchymal tumors. While many imaging modalities have been tried, it is now known that these tumors show high somatostatin receptor (SSTR) expression. Hence SSTR receptor imaging has emerged as a useful diagnostic tool. Here we present a series of TIO cases with clinical presentation and imaging characteristics.
肿瘤诱导的骨软化症（TIO）是严重致残性骨软化症的罕见病因，由低磷血症引起。基于生化参数的强烈临床怀疑可促使在体内寻找致病肿瘤。该疾病实体更常见于良性间充质肿瘤。虽然已经尝试了许多成像方式，但现在已知这些肿瘤显示出高生长抑素受体（SSTR）表达。因此，SSTR受体成像已成为一种有用的诊断工具。在此，我们展示了一系列具有临床表现和影像学特征的TIO病例。
