Comparison of the performance of magnetic targeting drug carriers prepared using two synthesis methods.

In this paper, two methods were used to prepare the magnetic targeting drug carrier FeO-PVA@SH, the step-by-step method and the one-pot method. The loading and release properties of the compound were measured. The results show that the FeO-PVA@SH prepared using both methods exhibited excellent drug delivery properties in an environment that simulates human body fluid (pH 7.2) and a lysosomal simulation (pH 4.7). In applications such as drug delivery, magnetic targeted drug carriers prepared by both methods demonstrated superparamagnetism, high fat solubility, high hydroxyl content, and good water solubility.