Department of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou 317000, Zhejiang, China.
Department of Pathology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou 317000, Zhejiang, China.
Contrast Media Mol Imaging. 2022 Apr 8;2022:7399255. doi: 10.1155/2022/7399255. eCollection 2022.
This study was aimed to evaluate the clinical efficacy of hemangioma resection in the treatment of infantile encephalofacial angiomatosis (Sturge-Weber syndrome, SWS) through magnetic resonance imaging (MRI) images, and intelligent algorithms were employed to process MRI images. A retrospective study of 45 children diagnosed with facial hemangioma admitted to hospital was conducted. Then, MRS images were acquired, and a mathematical model for MRI image denoising and reconstruction was constructed based on nonlocal similar block low-rank prior algorithms. The processing effect was assessed regarding the peak signal-to-noise ratio (PSNR) and structural similarity (SSIM). Finally, MRI images were collected to analyze the difference between the metabolites of N-acetylaspartic acid (NAA), creatine (Cr), choline (Cho), and their ratios in the lesions of the children before and after treatment. The improvement rate was analyzed through a twelve-month follow-up. The algorithm test results showed that compared with the classic K-singular value decomposition (K-SVD) denoising algorithm and the Sparse MRI reconstruction algorithm, the proposed algorithm processed MRI images more clearly and had more detailed information. The quantitative results showed that the PSNR and SSIM in the image processed by the algorithm proposed were remarkably large. The clinical treatment results showed that compared with those before treatment, the nCho level after treatment, the ratio of Cho/Cr and Cho/NAA were remarkably reduced, and the difference was remarkable ( < 0.05). The follow-up results showed that the considerable improvement rate was 88.89%, the postoperative organ remodeling rate was 17.78%, and the probability of reoperation was only 6.67%. In summary, the introduction of intelligent algorithms for denoising and reconstruction of MRI images can remarkably improve image quality and help doctors use image information to diagnose diseases and evaluate treatment effects. The hemangioma resection for the treatment of pediatric SWS had a high treatment improvement rate and was worthy of clinical adoption.
本研究旨在通过磁共振成像(MRI)图像评估血管瘤切除术治疗婴幼儿颜面血管瘤病(Sturge-Weber 综合征,SWS)的临床疗效,并采用智能算法处理 MRI 图像。对 45 例因面部血管瘤住院的患儿进行回顾性研究,获取 MRS 图像,基于非局部相似块低秩先验算法构建 MRI 图像去噪和重建的数学模型。评估处理效果,比较峰值信噪比(PSNR)和结构相似性(SSIM)。最后,采集 MRI 图像,分析患儿治疗前后病变区 N-乙酰天门冬氨酸(NAA)、肌酸(Cr)、胆碱(Cho)及其比值代谢物的差异,通过 12 个月的随访分析改善率。算法测试结果表明,与经典 K-奇异值分解(K-SVD)去噪算法和稀疏 MRI 重建算法相比,所提出的算法对 MRI 图像的处理更清晰,具有更详细的信息。定量结果表明,算法处理后的图像 PSNR 和 SSIM 显著增大。临床治疗结果表明,与治疗前相比,治疗后 nCho 水平、Cho/Cr 比值和 Cho/NAA 比值显著降低,差异具有统计学意义( < 0.05)。随访结果显示,治疗后有 88.89%的患儿有明显改善,术后器官重塑率为 17.78%,再次手术概率仅为 6.67%。总之,智能算法在 MRI 图像去噪和重建中的引入可以显著提高图像质量,帮助医生利用图像信息诊断疾病和评估治疗效果。血管瘤切除术治疗小儿 SWS 的治疗改善率高,值得临床推广。