Davari Seyedeh Dorsa, Rabbani Mohammad, Basti Afshin Akhondzadeh, Koohi Mohammad Kazem
Department of Food Science and Technology, Tehran North Branch, Islamic Azad University Tehran Iran.
Department of Marine Chemistry, Faculty of Marine Science and Technology, North Tehran Branch, Islamic Azad University Tehran Iran
RSC Adv. 2021 Jun 29;11(37):22983-22992. doi: 10.1039/d1ra00444a. eCollection 2021 Jun 25.
The aim of the current research is to develop a MSPE method for the determination of furfural in baby food and dry milk samples. In this regard, a novel magnetic porous carbon composite coated with poly(-phenylenediamine) was fabricated, characterized, and then applied to the preconcentration/extraction of furfurals from baby food and dry milk powder samples. Initially, magnetic nanoparticles (FeO) were synthesized, and then coated with a metal-organic framework layer named MIL-101(Fe). Afterward, the magnetic MIL-101(Fe) was subjected to calcination under a nitrogen atmosphere and magnetic porous carbon was achieved. Finally, a layer of poly(-phenylenediamine) was coated on the magnetic porous carbon. The structure of the nanocomposite was investigated with various methods, including FT-IR spectroscopy, electron microcopies (SEM and TEM), VSM, and XRD. The fabricated nanocomposite was applied in magnetic solid-phase extraction of furfural and hydroxymethyl furfural and their determination with liquid chromatography. The effect of experimental variables was explored by using an experimental design approach. The LODs and linear range for the target furfurals were 1.0-2.0 μg kg and 3.0-500 μg kg, respectively. The method's repeatability was explored using RSD values and was found to be in the range of 5.2-6.4% (one-day, = 5) and 9.1-10.8% (day to day, = 3). Eventually, this new method was employed for the extraction/quantification of target compounds in baby food and dry milk powder samples.
当前研究的目的是开发一种用于测定婴儿食品和奶粉样品中糠醛的磁性固相萃取（MSPE）方法。在这方面，制备了一种涂覆有聚（对苯二胺）的新型磁性多孔碳复合材料，对其进行了表征，然后将其应用于从婴儿食品和奶粉样品中预浓缩/萃取糠醛。首先，合成了磁性纳米颗粒（Fe3O4），然后用名为MIL-101(Fe)的金属有机框架层进行包覆。之后，将磁性MIL-101(Fe)在氮气气氛下进行煅烧，得到磁性多孔碳。最后，在磁性多孔碳上涂覆一层聚（对苯二胺）。用包括傅里叶变换红外光谱（FT-IR）、电子显微镜（扫描电子显微镜和透射电子显微镜）、振动样品磁强计（VSM）和X射线衍射（XRD）等多种方法研究了该纳米复合材料的结构。所制备的纳米复合材料应用于糠醛和羟甲基糠醛的磁性固相萃取及其液相色谱测定。通过实验设计方法探索了实验变量的影响。目标糠醛的检测限（LOD）和线性范围分别为1.0 - 2.0 μg/kg和3.0 - 500 μg/kg。使用相对标准偏差（RSD）值探索了该方法的重复性，发现其在5.2 - 6.4%（一天内，n = 5）和9.1 - 10.8%（不同天之间，n = 3）范围内。最终，该新方法用于婴儿食品和奶粉样品中目标化合物的萃取/定量分析。
