可持续的三嗪衍生季铵盐作为抗菌剂。
Sustainable triazine-derived quaternary ammonium salts as antimicrobial agents.
作者信息
Morandini Andrea, Spadati Emanuele, Leonetti Benedetta, Sole Roberto, Gatto Vanessa, Rizzolio Flavio, Beghetto Valentina
机构信息
Università Ca' Foscari di Venezia Via Torino 155 Venezia Mestre 30172 Italy
Brenta S.r.l. - Nine Trees Group. Viale Milano, 26 36075 Montecchio Maggiore Vicenza Italy.
出版信息
RSC Adv. 2021 Aug 19;11(45):28092-28096. doi: 10.1039/d1ra03455c. eCollection 2021 Aug 16.
The first examples of highly efficient antimicrobial triazine-derived bis imidazolium quaternary ammonium salts (TQAS) are reported. TQAS have been prepared with an easy, atom efficient, economically sustainable strategy and tested as antimicrobial agents, reaching MIC values below 10 mg L. Distinctively, TQAS have low MIC and low cytotoxicity.
报道了高效抗菌的三嗪衍生双咪唑鎓季铵盐（TQAS）的首个实例。TQAS已通过一种简便、原子经济、经济可持续的策略制备，并作为抗菌剂进行了测试，其最低抑菌浓度（MIC）值低于10 mg/L。值得注意的是，TQAS具有低MIC和低细胞毒性。
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