Limapichat Thanya, Supavajana Suvanun
Department of Emergency Medicine, Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Emerg Med Int. 2022 Apr 18;2022:6391141. doi: 10.1155/2022/6391141. eCollection 2022.
In most community-acquired pneumonia (CAP) treatment guidelines, the Pneumonia Severity Index (PSI) and CURB-65 are used as prognostic tools. Recently, simpler and more effective predictive tools for CAP treatment, such as the A-DROP scoring system, have been developed. However, no study has performed a comparative evaluation to identify the superior tool for predicting when patients can be discharged safely.
To compare the performances of A-DROP and CURB-65, simple predictive tools for CAP, based on 30-day death rates and 72-hour revisit rates for CAP following discharge from the emergency department (ED).
This single-center retrospective observational study enrolled patients who were at least 18 years old and diagnosed with CAP at the Songklanagarind Hospital ED from January 2015 to April 2021. Following a severity assessment using the A-DROP and CURB-65 scoring systems, the 30-day mortality rates and 72-hour revisit rates after discharge from the ED were compared.
A total of 408 patients were enrolled in this study. Six (1.47%) died within 30 days after presentation, whereas 29 (7.1%) returned to the ED within 72 hours after discharge. Most patients (72%) who revisited the ED were over the age of 65 years. The areas under the receiver operating characteristic curves for the prediction of 30-day mortality were 0.756 (95% confidence interval [CI]: 0.526-0.987) and 0.808 (95% CI: 0.647-0.970) for A-DROP and CURB-65, respectively. The areas under the receiver operating characteristic curves for the prediction of 72-hour revisit were 0.617 (95% confidence interval [CI]: 0.507-0.728) and 0.639 (95% CI: 0.536-0.743) for A-DROP and CURB-65, respectively.
A-DROP and CURB-65 yield similar results and can be used to assess low-risk patients with CAP for discharge from the ED. Older patients, even those with low-risk scores, should be particularly considered for admission to a short-term observation unit or ward.
在大多数社区获得性肺炎(CAP)治疗指南中,肺炎严重程度指数(PSI)和CURB-65被用作预后工具。最近,已经开发出了更简单、更有效的CAP治疗预测工具,如A-DROP评分系统。然而,尚无研究进行比较评估以确定预测患者何时可以安全出院的最佳工具。
基于急诊科(ED)出院后30天死亡率和72小时再就诊率,比较CAP的简单预测工具A-DROP和CURB-65的性能。
这项单中心回顾性观察研究纳入了2015年1月至2021年4月在宋卡纳加拉医院急诊科至少18岁且被诊断为CAP的患者。在使用A-DROP和CURB-65评分系统进行严重程度评估后,比较了ED出院后的30天死亡率和72小时再就诊率。
本研究共纳入408例患者。6例(1.47%)在就诊后30天内死亡,而29例(7.1%)在出院后72小时内返回ED。大多数返回ED的患者(72%)年龄超过65岁。A-DROP和CURB-65预测30天死亡率的受试者工作特征曲线下面积分别为0.756(95%置信区间[CI]:0.526-0.987)和0.808(95%CI:0.647-0.970)。A-DROP和CURB-65预测72小时再就诊的受试者工作特征曲线下面积分别为0.617(95%置信区间[CI]:0.507-0.728)和0.639(95%CI:0.536-0.743)。
A-DROP和CURB-所得结果相似,可用于评估CAP低风险患者是否可从ED出院。老年患者,即使是低风险评分患者,也应特别考虑入住短期观察病房或病房。