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空化作用和射频与冷冻溶脂对中心性肥胖患者瘦素调节的作用比较:一项随机对照研究。

Cavitation and radiofrequency versus cryolipolysis on leptin regulation in central obese subjects: A randomized controlled study.

机构信息

Basic Science Department, Faculty of Physical Therapy, Cairo University, Dokki, Giza, Egypt.

Basic Science Department, Faculty of Physical Therapy, Heliopolis University, Cairo, Egypt.

出版信息

Lasers Surg Med. 2022 Sep;54(7):955-963. doi: 10.1002/lsm.23555. Epub 2022 Apr 28.

DOI:10.1002/lsm.23555
PMID:35481595
Abstract

BACKGROUND AND OBJECTIVE

To investigate the efficacy of adding ultrasound cavitation and radiofrequency versus cryolipolysis to weight reduction program on leptin, insulin, waist circumference, skinfold, body weight in central obese subjects.

MATERIAL AND METHODS

Sixty centrally obese participants were randomly allocated into three equal groups. Subjects in the study group (I) received cavitation and radiofrequency plus dietary regimen, subjects in the second study group (II) received cryolipolysis in conjunction with the same diet program, and subjects in the control group (III) received the same dietary regimen only. Leptin, insulin level, waist circumference, skinfold, body weight, and body mass index were measured shortly before intervention techniques and 3 months afterward.

RESULTS

There were no statistically significant differences between cavitation plus radiofrequency and cryolipolysis on leptin and insulin levels after 3 months of intervention. However, statistically significant differences were found in waist circumference, skinfold, weight reduction, and body mass index in favor of the cavitation group (p < 0.05). In addition, both cavitation-radiofrequency and cryolipolysis were statistically significantly different than the diet alone in favor of the study groups (p < 0.05) in all the outcome measures. Furthermore, there were statistically significant differences in all outcome measures (p < 0.05) when comparing the baseline and postintervention results in each group except for leptin level in the diet group (p = 0.14).

CONCLUSION

Subjects who underwent cavitation plus radiofrequency had better improvement on waist circumference, skinfold, and body mass index than subjects who received cryolipolysis. However, no differences were found between cavitation plus radiofrequency and cryolipolysis on leptin and insulin levels.

摘要

背景与目的

研究在减肥计划中增加超声空化和射频与冷冻减脂相比对瘦素、胰岛素、腰围、皮褶厚度、中心性肥胖受试者体重的疗效。

材料与方法

将 60 名中心性肥胖受试者随机分为三组。研究组 I 接受超声空化和射频联合饮食方案,研究组 II 接受冷冻减脂联合相同的饮食方案,对照组 III 仅接受相同的饮食方案。在干预技术之前和 3 个月后测量瘦素、胰岛素水平、腰围、皮褶厚度、体重和体重指数。

结果

在干预 3 个月后,超声空化加射频与冷冻减脂在瘦素和胰岛素水平上无统计学差异。然而,在腰围、皮褶厚度、体重减轻和体重指数方面,超声空化组有统计学意义(p<0.05)。此外,与单独饮食相比,超声空化-射频和冷冻减脂在所有研究组的所有结果测量中均有统计学意义(p<0.05)。此外,除了饮食组的瘦素水平(p=0.14)外,在每组的基线和干预后结果之间的所有结果测量中都存在统计学差异(p<0.05)。

结论

与接受冷冻减脂的受试者相比,接受超声空化加射频的受试者在腰围、皮褶厚度和体重指数方面有更好的改善。然而,在瘦素和胰岛素水平方面,超声空化加射频与冷冻减脂之间没有差异。

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