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急性细菌性脑脊髓膜炎的多种影像学和临床表现。

Varied imaging and clinical presentations of acute bacterial cerebritis.

机构信息

Department of Radiology, Fortis Memorial Research Institute, Gurugram, Haryana, 122001, India.

Department of Neuroimaging and Interventional Radiology, National Institute for Mental Health and Neurosciences (NIMHANS), Bangalore, India.

出版信息

Emerg Radiol. 2022 Aug;29(4):791-799. doi: 10.1007/s10140-022-02051-3. Epub 2022 Apr 28.

DOI:10.1007/s10140-022-02051-3
PMID:35482173
Abstract

Infectious diseases affecting the central nervous system remain an important cause of morbidity and mortality in developing countries and in immunocompromised patients. Cerebritis refers to pyogenic inflammation of the brain parenchyma that may lead to abscess formation if left untreated. Cerebritis is an uncommon diagnosis as patients are usually diagnosed at the stage of abscess formation. We present three cases of bacterial cerebritis with different clinical manifestations and varied appearances on MRI. To our knowledge, only few case reports of bacterial cerebritis have been published in the literature, and imaging findings are not fully elucidated. These cases of bacterial cerebritis add valuable information to the existing literature and would be helpful in making the appropriate diagnosis of this uncommon condition that can be medically managed if diagnosed appropriately. We recommend that cerebritis should be considered in the differential diagnosis of such lesions.

摘要

中枢神经系统感染仍然是发展中国家和免疫功能低下患者发病率和死亡率的重要原因。脑脊髓炎是指化脓性脑实质炎症,如果不治疗,可能导致脓肿形成。由于患者通常在脓肿形成阶段被诊断出来,因此脑脊髓炎是一种罕见的诊断。我们介绍了三例具有不同临床表现和不同 MRI 表现的细菌性脑脊髓炎病例。据我们所知,文献中仅发表了少数几例细菌性脑脊髓炎的病例报告,影像学表现尚未完全阐明。这些细菌性脑脊髓炎的病例为现有文献提供了有价值的信息,并有助于对这种罕见疾病做出正确诊断,如果及早诊断,这种疾病可以通过药物治疗。我们建议在这些病变的鉴别诊断中应考虑脑脊髓炎。

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本文引用的文献

1
Differentiation of brain infection from necrotic glioblastoma using combined analysis of diffusion and perfusion MRI.使用弥散和灌注 MRI 的联合分析对脑感染与坏死性胶质母细胞瘤进行鉴别诊断。
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2
Early cerebritis resulting in a first-time seizure in an otherwise healthy young man.早期脑炎导致一名原本健康的年轻男子首次癫痫发作。
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Bacterial, Fungal, and Parasitic Infections of the Central Nervous System: Radiologic-Pathologic Correlation and Historical Perspectives.
中枢神经系统的细菌、真菌和寄生虫感染:放射学与病理学的相关性及历史观点
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Brain abscess.脑脓肿
N Engl J Med. 2014 Jul 31;371(5):447-56. doi: 10.1056/NEJMra1301635.
5
T2*-weighted MR angiography substantially increases the detection of hemorrhage in the wall of brain abscess: implications in clinical interpretation.T2*-加权磁共振血管造影术显著提高了脑脓肿壁出血的检出率:对临床解读的影响。
Neuroradiology. 2012 Jun;54(6):565-72. doi: 10.1007/s00234-011-0952-1. Epub 2011 Sep 14.
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Differentiation of infective from neoplastic brain lesions by dynamic contrast-enhanced MRI.通过动态对比增强磁共振成像鉴别感染性与肿瘤性脑病变
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Diagnosis of bacterial cerebellitis: diffusion imaging and proton magnetic resonance spectroscopy.细菌性小脑炎的诊断:扩散成像与质子磁共振波谱分析
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Diffusion-weighted imaging of cerebritis.脑脊髓炎的扩散加权成像
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[Septic-embolic and septic metastatic brain abscess].[脓毒性栓塞性和脓毒性转移性脑脓肿]
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10
Cranial magnetic resonance imaging findings in bacterial endocarditis: the neuroimaging spectrum of septic brain embolization demonstrated in twelve patients.细菌性心内膜炎的头颅磁共振成像表现:12例脓毒性脑栓塞的神经影像学谱
J Neuroimaging. 1999 Apr;9(2):78-84. doi: 10.1111/jon19999278.