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Methylartist:用于可视化纳米孔序列数据中修饰碱基的工具。

Methylartist: tools for visualizing modified bases from nanopore sequence data.

机构信息

Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, Australia.

Mater Research Institute-University of Queensland, Translational Research Institute, Woolloongabba, QLD 4102, Australia.

出版信息

Bioinformatics. 2022 May 26;38(11):3109-3112. doi: 10.1093/bioinformatics/btac292.

Abstract

SUMMARY

Methylartist is a consolidated suite of tools for processing, visualizing and analysing nanopore-derived modified base calls. All detectable methylation types (e.g. 5mCpG, 5hmC, 6mA) are supported, enabling integrated study of base pairs when modified naturally or as part of an experimental protocol.

AVAILABILITY AND IMPLEMENTATION

Methylartist is implemented in Python and is installable via PyPI and bioconda. Source code and test data are available at https://github.com/adamewing/methylartist.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

摘要

Methylartist 是一套用于处理、可视化和分析纳米孔衍生修饰碱基调用的综合工具。支持所有可检测的甲基化类型(例如 5mCpG、5hmC、6mA),可在修饰自然发生或作为实验方案一部分时,实现碱基对的综合研究。

可用性和实施

Methylartist 是用 Python 编写的,可以通过 PyPI 和 bioconda 安装。源代码和测试数据可在 https://github.com/adamewing/methylartist 上获得。

补充信息

补充数据可在 Bioinformatics 在线获得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62b8/9154218/909dcf480c35/btac292f1.jpg

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