Biomedical Engineering Laboratory, Escola Politécnica, University of São Paulo, São Paulo, Brazil.
PLoS One. 2022 Apr 28;17(4):e0267718. doi: 10.1371/journal.pone.0267718. eCollection 2022.
Transcutaneous spinal direct current stimulation (tsDCS) is an effective non-invasive spinal cord electrical stimulation technique to induce neuromodulation of local and distal neural circuits of the central nervous system (CNS). Applied to the spinal cord lumbosacral region, tsDCS changes electrophysiological responses of the motor, proprioceptive and nociceptive pathways, alters the performance of some lower limb motor tasks and can even modulate the behavior of supramedullary neuronal networks. In this study an experimental protocol was conducted to verify if tsDCS (5 mA, 20 minutes) of two different polarizations, applied over the lumbosacral region (tenth thoracic vertebrae (T10)), can induce changes in postural sway oscillations of young healthy individuals during quiet standing. A novel initialization of the electrical stimulation was developed to improve subject blinding to the different stimulus conditions including the sham trials. Measures of postural sway, both global and structural, were computed before, during and following the DC stimulation period. The results indicated that, for the adopted conditions, tsDCS did not induce statistically significant changes in postural sway of young healthy individuals during quiet standing.
经皮脊髓直流电刺激（tsDCS）是一种有效的非侵入性脊髓电刺激技术，可诱导中枢神经系统（CNS）局部和远端神经回路的神经调节。应用于腰骶脊髓区域，tsDCS 改变运动、本体感觉和伤害感受通路的电生理反应，改变一些下肢运动任务的表现，甚至可以调节上运动神经元网络的行为。在这项研究中，进行了一项实验方案，以验证两种不同极性的 tsDCS（5 mA，20 分钟）施加于腰骶区域（第 10 胸椎（T10））是否可以在安静站立期间诱导年轻健康个体的姿势摆动振荡的变化。开发了一种新的电刺激初始化方法，以提高对不同刺激条件的受试者盲目性，包括假刺激试验。在直流刺激期间和之后，计算了姿势摆动的全局和结构测量值。结果表明，在采用的条件下，tsDCS 并未在安静站立期间诱导年轻健康个体的姿势摆动产生统计学上显著的变化。
