Wang Yuhong, Dong Tingting, Li Xiahuang, Zhao Huiyun, Yang Lili, Xu Rui, Fu Yi, Li Li, Gai Xuesong, Qin Dongdong
Department of Rehabilitation Medicine, The First People's Hospital of Yunnan Province, Kunming, China.
Department of Neurosurgery, Mengzi People's Hospital, Mengzi, China.
Front Neurol. 2023 Jul 18;14:1219590. doi: 10.3389/fneur.2023.1219590. eCollection 2023.
Traumatic or non-traumatic spinal cord injury (SCI) can lead to severe disability and complications. The incidence of SCI is high, and the rehabilitation cycle is long, which increases the economic burden on patients and the health care system. However, there is no practical method of SCI treatment. Recently, transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique, has been shown to induce changes in plasticity in specific areas of the brain by regulating the activity of neurons in the stimulation site and its functionally connected networks. TMS is a new potential method for the rehabilitation of SCI and its complications. In addition, TMS can detect the activity of neural circuits in the central nervous system and supplement the physiological evaluation of SCI severity. This review describes the pathophysiology of SCI as well as the basic principles and classification of TMS. We mainly focused on the latest research progress of TMS in the physiological evaluation of SCI as well as the treatment of motor dysfunction, neuropathic pain, spasticity, neurogenic bladder, respiratory dysfunction, and other complications. This review provides new ideas and future directions for SCI assessment and treatment.
创伤性或非创伤性脊髓损伤(SCI)可导致严重残疾和并发症。SCI的发病率很高,康复周期很长,这增加了患者和医疗保健系统的经济负担。然而,目前尚无实用的SCI治疗方法。最近,经颅磁刺激(TMS)作为一种非侵入性脑刺激技术,已被证明可通过调节刺激部位及其功能连接网络中的神经元活动,诱导大脑特定区域的可塑性变化。TMS是一种用于SCI及其并发症康复的新的潜在方法。此外,TMS可检测中枢神经系统中神经回路的活动,并补充SCI严重程度的生理评估。本综述描述了SCI的病理生理学以及TMS的基本原理和分类。我们主要关注TMS在SCI生理评估以及运动功能障碍、神经性疼痛、痉挛、神经源性膀胱、呼吸功能障碍和其他并发症治疗方面的最新研究进展。本综述为SCI评估和治疗提供了新的思路和未来方向。