急性和慢性主观性耳鸣的临床特征及心理声学分析

Clinical characteristics and psychoacoustic analysis of acute and chronic subjective tinnitus.

作者信息

Zhang Haopeng, Ji Lin, Wang Lihua, Yin Ziming, Cen Jingtu, Guo Yu

机构信息

Department of Otolaryngology Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine Shanghai China.

School of Medical Instrument and Food Engineering University of Shanghai for Science and Technology Shanghai China.

出版信息

Laryngoscope Investig Otolaryngol. 2023 Mar 6;8(2):546-553. doi: 10.1002/lio2.1037. eCollection 2023 Apr.

DOI:10.1002/lio2.1037

PMID:37090863

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10116969/

Abstract

OBJECTIVE

This study aimed to understand the demographics, clinical characteristics, and psychoacoustic status of subjective tinnitus patients to explore the factors associated with acute and chronic tinnitus in the general hospitals of Shanghai.

METHODS

A cross-sectional study was conducted to investigate the clinical characteristics and psychoacoustic status of subjective tinnitus patients with history greater than 1 month. Data were collected during January 2021 and January 2022 from eight general hospitals in five districts of Shanghai, China. All patients accepted questionnaires and acoustic examination, then SPSS 22.0 and GraphPad Prism 8.0.2 were applied for data analysis.

RESULTS

Among the 359 tinnitus patients, 126 cases were diagnosed with acute tinnitus, 58 cases were subacute tinnitus, and 175 cases were chronic tinnitus. Patients with acute and chronic tinnitus differed in terms of side of tinnitus, hearing loss, frequency of tinnitus, severity of tinnitus, anxiety, depression, and sleep status. Different characteristics were included in the multivariate ordinal logistic regression analysis. Persistent tinnitus (OR = 2.00, = .008), high frequency hearing loss (OR = 4.77, < .001), depression (OR = 1.23, < .001) were found to be positively associated with the course of tinnitus. Unilateral tinnitus (OR = 0.48, = .003), mild (OR = 0.29, = .001) and moderate (OR = 0.46, = .038) hearing loss, VAS scores (OR = 0.82, = .032), anxiety (OR = 0.81, < .001), THI scores (OR = 0.98, = .002), and sleep disorders (OR = 0.94, = .025) were found to be negatively associated with the course of tinnitus.

CONCLUSION

Patients with acute tinnitus were at greater risk for anxiety, sleep disturbances, and exacerbation of tinnitus perception, and those with chronic tinnitus were at greater risk for depression.

LAY SUMMARY

Our study demonstrated that patients with acute tinnitus were at greater risk for anxiety, sleep disturbances, and exacerbation of tinnitus perception, and those with chronic tinnitus were at greater risk for depression.

摘要

目的

本研究旨在了解主观性耳鸣患者的人口统计学特征、临床特征及心理声学状况，以探索上海市综合医院中与急性和慢性耳鸣相关的因素。

方法

进行一项横断面研究，调查耳鸣病史超过1个月的主观性耳鸣患者的临床特征及心理声学状况。于2021年1月至2022年1月期间，在中国上海五个区的八家综合医院收集数据。所有患者均接受问卷调查及听力学检查，然后应用SPSS 22.0和GraphPad Prism 8.0.2进行数据分析。

结果

在359例耳鸣患者中，126例被诊断为急性耳鸣，58例为亚急性耳鸣，175例为慢性耳鸣。急性和慢性耳鸣患者在耳鸣侧别、听力损失、耳鸣频率、耳鸣严重程度、焦虑、抑郁及睡眠状况方面存在差异。多因素有序逻辑回归分析纳入了不同特征。发现持续性耳鸣（OR = 2.00，P = 0.008）、高频听力损失（OR = 4.77，P < 0.001）、抑郁（OR = 1.23，P < 0.001）与耳鸣病程呈正相关。单侧耳鸣（OR = 0.48，P = 0.003）、轻度（OR = 0.29，P = 0.001）和中度（OR = 0.46，P = 0.038）听力损失、视觉模拟评分（VAS）（OR = 0.82，P = 0.032）、焦虑（OR = 0.81，P < 0.001）、耳鸣 handicap 量表（THI）评分（OR = 0.98，P = 0.002）及睡眠障碍（OR = 0.94，P = 0.025）与耳鸣病程呈负相关。