Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan.
Department of Physical Medicine and Rehabilitation, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Sci Rep. 2022 Apr 28;12(1):6920. doi: 10.1038/s41598-022-10622-0.
Six-minute walk distance (6MWD) of 300 and 400 m are important targets of functional capacity. The present study was performed to determine cutoff values of physical function associated with 6MWD < 300 m and < 400 m in elderly patients with heart failure (HF). 6MWD, handgrip strength, quadriceps isometric strength (QIS), one-leg standing time (OLST), and 5-times sit-to-stand (5STS) before hospital discharge were evaluated in 1001 patients > 65 years (median age, 75: interquartile range, 71-80, 607 men) with HF. 6MWD < 300 and < 400 m were seen in 323 patients (32.3%) and 658 patients (65.7%), respectively. Handgrip strength, QIS, OLST, and 5STS were associated with 6MWD < 300 and < 400 m, respectively (P < 0.001). The cutoff values of handgrip strength, QIS, OLST, and 5STS were 18.9 kg, 35.0% body mass (BM), 9.1 s, and 9.5 s for 6MWD < 300 m, and 21.9 kg, 40.0% BM, 12.0 s, and 8.8 s for < 400 m, respectively. The cutoff values of physical function could be used to set cardiac rehabilitation goals and limiting determinants of reduced functional capacity in a clinical setting in elderly patients with HF.
6 分钟步行距离（6MWD）达到 300 米和 400 米是功能能力的重要目标。本研究旨在确定与心力衰竭（HF）老年患者 6MWD<300 米和<400 米相关的身体功能的截止值。在 1001 名年龄>65 岁（中位数年龄 75：四分位距 71-80，607 名男性）的 HF 患者出院前评估了 6MWD、握力、股四头肌等长力量（QIS）、单腿站立时间（OLST）和 5 次坐立（5STS）。323 名（32.3%）和 658 名（65.7%）患者的 6MWD<300 米和<400 米。握力、QIS、OLST 和 5STS 分别与 6MWD<300 米和<400 米相关（P<0.001）。6MWD<300 米的握力、QIS、OLST 和 5STS 的截止值分别为 18.9kg、35.0%体重（BM）、9.1s 和 9.5s，<400 米的截止值分别为 21.9kg、40.0%BM、12.0s 和 8.8s。在老年 HF 患者的临床环境中，身体功能的截止值可用于设定心脏康复目标和限制功能能力降低的决定因素。
