Su Wei, Chen Hongguang, Gao Ying, Qin Qin, Liu Boqi, Deng Wei, Wang Yuhan, Zhang Gaolei, Liu Xiaoyan
Department of Dermatology, Capital Institute of Pediatrics, No. 2 YaBao Street, ChaoYang District, Beijing, 100020, China.
Key Laboratory of Mental Health, Peking University Sixth Hospital, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University Institute of Mental Health, Ministry of Health (Peking University), Beijing, China.
Ann Gen Psychiatry. 2022 Apr 28;21(1):12. doi: 10.1186/s12991-022-00389-z.
The prevalence of anxiety and depression symptoms among caretakers of children with atopic dermatitis (AD) and associated factors is unclear. The study was designed to explore anxiety and depression symptoms among caretakers of AD, and screen factors associated with anxiety and depression symptoms.
A total of 901 children with AD and their caretakers were continuously enrolled and interviewed at dermatology department of Capital Institute of Pediatrics, Beijing, China. Children's medication was administered by their caretakers. Caretakers' anxiety and depression symptoms were evaluated by Hamilton Depression Rating Scale-17 and Hamilton Depression Rating Scale, while medication compliance was evaluated and divided into poor (< 6 points), moderate (6-7 points), and good (> 7 points) by Morisky Medication Adherence Scale. Multilevel ordered logistic regression was used to screen factors associated with caretakers' anxiety and depression.
Among caretakers, 41.5% had anxiety symptoms, 39.6% had depression symptoms, 51.4% have any of the two and 29.7% had both of the two. Factors associated with caretakers' anxiety symptoms included longer duration of the illness (OR, 0.99, 95% CI 0.98-0.99) and taking care of children with severe AD (OR, 2.55, 95% CI 1.43-4.55). Factors associated with caretakers' depression symptoms included higher educational level (OR, 0.56, 95% CI 0.39-0.80), taking care of children with moderate (OR, 2.01, 95% CI 1.15-3.50) and severe AD (OR, 3.99, 95% CI 2.10-7.59) and poor medication compliance (OR, 3.45, 95% CI 1.13-10.56).
Prevalence of anxiety and depression symptoms among caretakers of AD were high. Attention should be paid to caretakers of AD at higher risk for those psychological problems.
特应性皮炎(AD)患儿照料者焦虑和抑郁症状的患病率及相关因素尚不清楚。本研究旨在探讨AD患儿照料者的焦虑和抑郁症状,并筛查与焦虑和抑郁症状相关的因素。
在中国北京首都儿科研究所皮肤科连续纳入901例AD患儿及其照料者并进行访谈。患儿用药由其照料者管理。采用汉密尔顿抑郁量表17项版和汉密尔顿焦虑量表评估照料者的焦虑和抑郁症状,同时采用Morisky药物依从性量表评估用药依从性,并分为差(<6分)、中(6-7分)、好(>7分)。采用多水平有序逻辑回归分析筛查与照料者焦虑和抑郁相关的因素。
照料者中,41.5%有焦虑症状,39.6%有抑郁症状,51.4%有其中一种症状,29.7%两种症状都有。与照料者焦虑症状相关的因素包括病程较长(比值比[OR],0.99,95%置信区间[CI] 0.98-0.99)和照料重度AD患儿(OR,2.55,95% CI 1.43-4.55)。与照料者抑郁症状相关的因素包括教育程度较高(OR,0.56,95% CI 0.39-0.80)、照料中度(OR,2.01,95% CI 1.15-3.50)和重度AD患儿(OR,3.99,95% CI 2.10-7.59)以及用药依从性差(OR,3.45,95% CI 1.13-10.56)。
AD患儿照料者焦虑和抑郁症状的患病率较高。应关注那些存在这些心理问题高风险的AD患儿照料者。