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台湾地区焦虑和抑郁风险与特应性皮炎严重程度之间的相关性:一项横断面研究。

Correlation between anxiety and depression risk and atopic dermatitis severity in Taiwan: A cross-sectional study.

作者信息

Hsu Chia-Jung, Shen Dereck, Chan Tom C, Cho Yung-Tsu, Tang Chao-Hsiun, Chu Chia-Yu

机构信息

Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

School of Health Care Administration, Taipei Medical University, Taipei, Taiwan.

出版信息

JAAD Int. 2022 Feb 22;7:22-30. doi: 10.1016/j.jdin.2021.12.008. eCollection 2022 Jun.

Abstract

BACKGROUND

Limited studies on atopic dermatitis (AD) have investigated the possible covariance of sociodemographic factors with the Hospital Anxiety and Depression Scale (HADS).

OBJECTIVE

This study aimed to examine the possible covariance between AD severity and HADS scores of patients in Taiwan.

METHODS

Patients with AD from a medical center and 2 regional hospitals in Taiwan were enrolled in this cross-sectional study from April 2018 to April 2019. AD severity was measured using the "scoring atopic dermatitis" index, and anxiety and depression were screened based on HADS.

RESULTS

A total of 200 patients were included. After correcting for sociodemographic variables, significantly more borderline (≥8) and abnormal (≥11) cases of anxiety/depression ( < .05) were noted in patients with moderate-to-severe AD.

LIMITATIONS

First, the cross-sectional study design cannot show causality. Second, baseline data, including a history of underlying cancer or previous psychiatric disorder, were not obtained in the questionnaire and may confound the HADS scores. Finally, a standardized psychiatric clinical interviews study design should be used for higher accuracy in the assessment of psycho-comorbidities.

CONCLUSION

Higher anxiety and depression risks were noted in patients with moderate-to-severe AD. Except for psychosomatic symptoms, all kinds of anxiety and depression symptoms occurred more frequently in patients with moderate-to-severe AD.

摘要

背景

关于特应性皮炎(AD)的研究有限,尚未探究社会人口学因素与医院焦虑抑郁量表(HADS)之间可能存在的协方差。

目的

本研究旨在探讨台湾地区AD患者的病情严重程度与HADS评分之间可能存在的协方差。

方法

2018年4月至2019年4月,对台湾一家医学中心和两家地区医院的AD患者进行了这项横断面研究。采用“特应性皮炎评分”指数评估AD严重程度,并根据HADS筛查焦虑和抑郁情况。

结果

共纳入200例患者。校正社会人口学变量后,中度至重度AD患者中焦虑/抑郁的临界(≥8)和异常(≥11)病例显著更多(<0.05)。

局限性

首先,横断面研究设计无法显示因果关系。其次,问卷中未获取包括潜在癌症病史或既往精神疾病史在内的基线数据,可能会混淆HADS评分。最后,为了更准确地评估精神共病,应采用标准化的精神科临床访谈研究设计。

结论

中度至重度AD患者的焦虑和抑郁风险较高。除心身症状外,中度至重度AD患者各种焦虑和抑郁症状的发生频率更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c7d/8873920/25013546550e/gr1.jpg

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本文引用的文献

1
Prevalence of baseline comorbidities in patients with atopic dermatitis: A population-based cohort study in Taiwan.
JAAD Int. 2020 Jun 12;1(1):50-58. doi: 10.1016/j.jdin.2020.05.002. eCollection 2020 Jul.
2
Symptoms and diagnosis of anxiety and depression in atopic dermatitis in U.S. adults.
Br J Dermatol. 2019 Sep;181(3):554-565. doi: 10.1111/bjd.17683. Epub 2019 Mar 5.
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