Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Department of Chemistry, Shiraz University, Shiraz, Iran.
Biotechnol Appl Biochem. 2023 Feb;70(1):318-329. doi: 10.1002/bab.2354. Epub 2022 Jun 21.
Testosterone is an anabolic steroid and a major sex hormone in males. It plays vital roles, including developing the testis, penis, and prostate, increasing muscle and bone, and sperm production. In both men and women, testosterone levels should be in normal ranges. Besides, testosterone and its analogs are major global contributors to doping in sport. Due to the importance of testosterone testing, novel, accurate biosensors have been developed. This review summarizes the various methods for testosterone measurement. Also, recent optical and electrochemical approaches for the detection of testosterone and its analogs have been discussed.
睾酮是一种合成代谢类固醇，也是男性的主要性激素。它发挥着至关重要的作用，包括发育睾丸、阴茎和前列腺，增加肌肉和骨骼，以及精子的产生。在男性和女性中，睾酮水平应处于正常范围。此外，睾酮及其类似物是运动中兴奋剂的主要全球性贡献者。由于睾酮测试的重要性，已经开发出了新型、准确的生物传感器。本综述总结了睾酮测量的各种方法。此外，还讨论了最近用于检测睾酮及其类似物的光学和电化学方法。
