School of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering (Ministry of Education), Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, PR China; College of Food Science and Technology, Key Laboratory of Food Processing and Quality Control, Nanjing Agricultural University, Nanjing 210095, PR China.
School of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering (Ministry of Education), Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, PR China.
Biosens Bioelectron. 2018 May 30;106:122-128. doi: 10.1016/j.bios.2018.01.049. Epub 2018 Feb 1.
Food safety always remains a grand global challenge to human health, especially in developing countries. To solve food safety pertained problems, numerous strategies have been developed to detect biological and chemical contaminants in food. Among these approaches, nanomaterials-based biosensors provide opportunity to realize rapid, sensitive, efficient and portable detection, overcoming the restrictions and limitations of traditional methods such as complicated sample pretreatment, long detection time, and relying on expensive instruments and well-trained personnel. In this review article, we provide a cross-disciplinary perspective to review the progress of nanomaterials-based biosensors for the detection of food contaminants. The review article is organized by the category of food contaminants including pathogens/toxins, heavy metals, pesticides, veterinary drugs and illegal additives. In each category of food contaminant, the biosensing strategies are summarized including optical, colorimetric, fluorescent, electrochemical, and immune- biosensors; the relevant analytes, nanomaterials and biosensors are analyzed comprehensively. Future perspectives and challenges are also discussed briefly. We envision that our review could bridge the gap between the fields of food science and nanotechnology, providing implications for the scientists or engineers in both areas to collaborate and promote the development of nanomaterials-based biosensors for food safety detection.
食品安全一直是人类健康的全球性重大挑战，尤其是在发展中国家。为了解决食品安全相关问题，已经开发出许多策略来检测食品中的生物和化学污染物。在这些方法中，基于纳米材料的生物传感器提供了实现快速、灵敏、高效和便携检测的机会，克服了传统方法的限制和局限性，例如复杂的样品预处理、检测时间长、依赖昂贵的仪器和经过良好培训的人员。在这篇综述文章中，我们从跨学科的角度综述了用于检测食品污染物的基于纳米材料的生物传感器的进展。综述文章按照食品污染物的类别组织，包括病原体/毒素、重金属、农药、兽药和非法添加剂。在每一类食品污染物中，总结了包括光学、比色法、荧光、电化学和免疫生物传感器在内的生物传感策略；对相关分析物、纳米材料和生物传感器进行了全面分析。还简要讨论了未来的展望和挑战。我们设想，我们的综述可以弥合食品科学和纳米技术领域之间的差距，为这两个领域的科学家或工程师提供合作和促进用于食品安全检测的基于纳米材料的生物传感器发展的启示。
