Department of General Surgery, University of Health Sciences, Gaziosmanpasa Training and Research Hospital, İstanbul-Turkey.
Department of Pathology, University of Health Sciences, Gaziosmanpasa Training and Research Hospital, İstanbul-Turkey.
Ulus Travma Acil Cerrahi Derg. 2022 Mar;28(3):352-360. doi: 10.14744/tjtes.2021.86032.
Appendix neoplasms are rare tumors of the gastrointestinal system. Appendiceal adenocarcinoma, appendiceal mucinous neoplasm, and neuroendocrine tumors (NETs) are the most encountered appendix-related neoplasms. The patients are usually got diagnosed after histopathological examination. This study aimed to explore the epidemiology, pathological subtypes, and treatment modalities of appendix neoplasms.
A retrospective examination was made with 2821 patients who underwent appendectomy between April 2010 and August 2020. Demographic, clinical, radiological, surgical findings, and histopathological results were collected from the patient files.
Appendix neoplasms were detected in 1.06% of the patients included in the study. The mean age was 44.6±17.5 (17-83) years. Eight NETs, seven adenocarcinomas, fourteen mucinous neoplasms, and one neuroma were diagnosed with patients.
Appendiceal neoplasms are generally asymptomatic and often diagnosed with postoperative histopathological ex-amination. If the result is adenocarcinoma, right hemicolectomy recommends. Treatment of NETs depends on factors such as tumor size, location, mesoappendix invasion, and lymph node involvement. In the presence of mucinous neoplasm, surgical intervention is determined according to the pathological subtype and involvement of mesoappendix. The need for additional surgical intervention or medical treatment for patients with tumor, histopathological results must be followed carefully after appendectomy.
阑尾肿瘤是胃肠道罕见肿瘤。阑尾腺癌、阑尾黏液性肿瘤和神经内分泌肿瘤（NETs）是最常见的阑尾相关肿瘤。患者通常在组织病理学检查后确诊。本研究旨在探讨阑尾肿瘤的流行病学、病理亚型和治疗方式。
对 2010 年 4 月至 2020 年 8 月期间接受阑尾切除术的 2821 例患者进行回顾性检查。从患者病历中收集人口统计学、临床、影像学、手术发现和组织病理学结果。
研究纳入的患者中，阑尾肿瘤的检出率为 1.06%。平均年龄为 44.6±17.5（17-83）岁。诊断出 8 例 NETs、7 例腺癌、14 例黏液性肿瘤和 1 例神经瘤。
阑尾肿瘤通常无症状，常在术后组织病理学检查中确诊。如果结果为腺癌，则推荐行右半结肠切除术。NETs 的治疗取决于肿瘤大小、位置、阑尾系膜侵犯和淋巴结受累等因素。存在黏液性肿瘤时，根据病理亚型和阑尾系膜累及情况决定是否进行手术干预。对于肿瘤患者，术后必须密切随访肿瘤、组织病理学结果，必要时进行其他手术干预或药物治疗。
