Hansson P, Ekblom A
Appl Neurophysiol. 1986;49(3):155-65. doi: 10.1159/000100140.
The pain-relieving effect of vibratory stimulation, using different stimulus parameters, and placebo stimulation in acute orofacial pain is reported. The influence of 10-, 100-, and 200-Hz vibrations on pain reduction was studied in 96 patients; two different probe sizes were used. 54 out of 76 patients, receiving vibrations at any of the above frequencies, reported relief of pain to some extent, while only 6 out of 20 patients receiving placebo treatment experienced pain alleviation. No significant differences were found between the different frequencies and probe sizes used regarding the pain-relieving effect. However, placebo stimulation was significantly less effective than any kind of vibratory stimulation. Induction time for pain relief was significantly shorter using the larger probe as compared to using the smaller probe, regardless of frequency. The results indicate that the vibratory frequency (10-200 Hz) for activation of pain-inhibitory mechanisms is not critical in acute orofacial pain. Also, spatial summation from vibration-sensitive afferents seems to be of importance for a fast activation of the inhibitory systems.
据报道，使用不同刺激参数的振动刺激及安慰剂刺激对急性口腔面部疼痛的止痛效果。对96名患者研究了10赫兹、100赫兹和200赫兹振动对减轻疼痛的影响；使用了两种不同尺寸的探头。在76名接受上述任何一种频率振动的患者中，有54名报告疼痛在一定程度上得到缓解，而在20名接受安慰剂治疗的患者中，只有6名疼痛得到缓解。在所使用的不同频率和探头尺寸之间，未发现止痛效果有显著差异。然而，安慰剂刺激的效果明显低于任何一种振动刺激。无论频率如何，使用较大探头时疼痛缓解的诱导时间明显短于使用较小探头时。结果表明，在急性口腔面部疼痛中，激活疼痛抑制机制的振动频率（10 - 200赫兹）并不关键。此外，来自对振动敏感的传入神经的空间总和似乎对抑制系统的快速激活很重要。
