National School of Development, Peking University, Beijing, China.
Lost Child's Vision Project, Sydney, Australia.
JAMA Netw Open. 2022 Apr 1;5(4):e229545. doi: 10.1001/jamanetworkopen.2022.9545.
Myopia in youths is an increasingly common global problem, associated with significant social and economic burden worldwide.
To explore the association of school education with myopia and investigate its scale, controlling confounding factors, such as age and socioeconomic status.
DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study was conducted from July 2019 to December 2020 using regression discontinuity (RD) based on the Compulsory Education Law to examine the complex association of school education with myopia. Participants were youths from grades 1 to 12 before tertiary or university studies in China, including individuals from 815 primary schools, 373 junior high schools, and 145 senior high schools. Data were analyzed from February through June 2021.
Participants born earlier in a year (ie, January to August) were assigned 1 more year of education and were considered to be in the treated group, while participants born September to December were considered to be in the control group.
Differences in mean spherical equivalent refractive error (MSE) and uncorrected visual acuity (UVA) between treated and control groups were calculated.
Among a mean (SD) of 812 979 (55 953) participants across 5 surveys survey (mean SD 44.9% [0.5%] female participants; mean [SD] age, 11.19 [2.60] years), the mean (SD) MSE was -1.30 (2.93) diopters and mean (SD) UVA was 4.77 (0.34) points. Every additional year at school was associated with an decrease in MSE of -0.17 diopters/y (95% CI, -0.22 to -0.11 diopters/y) and a decrease in UVA of -0.03 points/y (95% CI, -0.04 to -0.02 points/y), which accounts for nearly 66.4% (95% CI, 85.9% to 43.0%) and 78.9% (95% CI, 102.6% to 55.3%) of changes of MSE and UVA, respectively, among all factors for youths. The greatest MSE shifts occurred in grades 3 and 7 (eg, for the June 2019 census, the RD was -0.26 diopters/y [95% CI, -0.33 to -0.20 diopters/y] for grade 3 and -0.41 diopters/y [95% CI, -0.66 to -0.15 diopters/y] for grade 7).
These findings suggest that receiving more years of education, instead of age, may be a risk factor associated with myopia progression in youths.
青少年近视是一个日益普遍的全球性问题,与全球范围内的重大社会和经济负担有关。
探讨学校教育与近视的关系,并在控制年龄和社会经济地位等混杂因素的情况下,研究其规模。
设计、地点和参与者:这是一项从 2019 年 7 月至 2020 年 12 月进行的横断面研究,采用基于义务教育法的回归不连续性 (RD) 来研究学校教育与近视的复杂关系。参与者为中国大学前的 1 至 12 年级的青少年,包括来自 815 所小学、373 所初中和 145 所高中的个体。数据分析于 2021 年 2 月至 6 月进行。
一年中较早出生的参与者(即 1 月至 8 月)被分配 1 年的教育,被视为治疗组,而 9 月至 12 月出生的参与者被视为对照组。
计算治疗组和对照组之间平均球镜等效折射误差(MSE)和未矫正视力(UVA)的差异。
在 5 次调查(平均 [SD] 44.9%[0.5%]女性参与者;平均 [SD] 年龄 11.19[2.60]岁)中,共有 812979 名(55953 名)参与者,平均(SD)MSE 为-1.30(2.93)屈光度,平均(SD)UVA 为 4.77(0.34)点。每增加 1 年的学业与 MSE 降低 0.17 屈光度/年(95%CI,-0.22 至 -0.11 屈光度/年)和 UVA 降低 0.03 点/年(95%CI,-0.04 至 -0.02 点/年)相关,分别占 MSE 和 UVA 变化的近 66.4%(95%CI,85.9%至 43.0%)和 78.9%(95%CI,102.6%至 55.3%),这是青少年所有因素中 MSE 和 UVA 变化的主要原因。MSE 变化最大的发生在 3 年级和 7 年级(例如,对于 2019 年 6 月的普查,3 年级的 RD 为-0.26 屈光度/年[95%CI,-0.33 至 -0.20 屈光度/年],7 年级为-0.41 屈光度/年[95%CI,-0.66 至 -0.15 屈光度/年])。
这些发现表明,接受更多年的教育而不是年龄可能是青少年近视进展的一个风险因素。