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新冠感染全身应用莫西沙星治疗后出现双侧急性虹膜色素脱失(BADI)

Bilateral Acute Depigmentation of Iris (BADI) Post COVID Infection following Systemic Moxifloxacin Therapy.

机构信息

Department of Uvea & Medical Retina, Sankara Nethralaya, Kolkata, India.

Department of Glaucoma, Sankara Nethralaya, Kolkata, India.

出版信息

Ocul Immunol Inflamm. 2023 Aug;31(6):1210-1212. doi: 10.1080/09273948.2022.2069126. Epub 2022 Apr 29.

DOI:10.1080/09273948.2022.2069126
PMID:35486641
Abstract

PURPOSE

To report a case of BADI post Covid infection following systemic moxifloxacin therapy.

METHODS

Observational case study.

CASE REPORT

A 28-year-old female presented to us with complaints of redness and pain in the right eye since 5 days. History revealed use of systemic moxifloxacin for covid infection. She was managed with topical corticosteroids and cycloplegics following a diagnosis of BADI.

CONCLUSION

Bilateral acute depigmentation of iris (BADI) is a rare disease entity associated with the release of iris pigments. Various underlying aetiologies have been associated with the same. Although BADI is a benign, self-limiting disorder, it needs to be differentiated with other potential severe clinical entities. SARS-CoV2 has been associated with various ocular manifestations. However, to the best of our knowledge, BADI has never been associated with COVID infection yet. We report a case of BADI in a young healthy Asian middle - aged female 3 months after an acute COVID infection.

摘要

目的

报告 1 例新冠感染后全身应用莫西沙星治疗后发生 BADI 的病例。

方法

观察性病例研究。

病例报告

1 例 28 岁女性,因右眼发红和疼痛 5 天就诊。病史提示因新冠感染全身应用莫西沙星。诊断为 BADI 后,给予局部皮质类固醇和睫状肌麻痹剂治疗。

结论

双侧急性虹膜色素脱失(BADI)是一种罕见的疾病实体,与虹膜色素释放有关。各种潜在病因与之相关。尽管 BADI 是一种良性、自限性疾病,但需要与其他潜在严重的临床实体相鉴别。SARS-CoV2 与各种眼部表现有关。然而,据我们所知,BADI 从未与 COVID 感染有关。我们报告了一例急性 COVID 感染后 3 个月,在一位年轻健康的亚洲中年女性中发生 BADI 的病例。

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引用本文的文献

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Ophthalmol Ther. 2025 May;14(5):1157-1168. doi: 10.1007/s40123-025-01135-w. Epub 2025 Apr 2.
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Bilateral acute depigmentation of the iris determined in two cases after COVID-19 infection.两例 COVID-19 感染后出现的双侧急性虹膜色素脱失。
Indian J Ophthalmol. 2023 Mar;71(3):1030-1032. doi: 10.4103/ijo.IJO_949_22.
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Bilateral Acute Depigmentation of Iris (BADI) and Bilateral Acute Iris Transillumination (BAIT)-An Update.
双侧急性虹膜退色症(BADI)和双侧急性虹膜光透过性(BAIT)-更新。
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Commentary: COVID-19-related bilateral acute depigmentation of iris with ocular hypertension.评论:与 COVID-19 相关的双侧虹膜急性色素脱失伴眼压升高。
Indian J Ophthalmol. 2022 Aug;70(8):3140. doi: 10.4103/ijo.IJO_1297_22.