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生活方式、行为和环境改变在炎症性肠病患者管理中的作用:国际炎症性肠病组织共识。

Lifestyle, behaviour, and environmental modification for the management of patients with inflammatory bowel diseases: an International Organization for Study of Inflammatory Bowel Diseases consensus.

机构信息

Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Division of Gastroenterology & Hepatology, University of Calgary, Calgary, AB, Canada.

出版信息

Lancet Gastroenterol Hepatol. 2022 Jul;7(7):666-678. doi: 10.1016/S2468-1253(22)00021-8. Epub 2022 Apr 27.

DOI:10.1016/S2468-1253(22)00021-8
PMID:35487235
Abstract

Environmental and lifestyle factors play an important role in the natural history of Crohn's disease and ulcerative colitis. A group of international experts from the International Organization for the Study of Inflammatory Bowel Diseases voted on a series of consensus statements to inform the management of inflammatory bowel disease (IBD). The recommendations include avoiding traditional cigarette smoking in patients with Crohn's disease or ulcerative colitis, screening for symptoms of depression, anxiety, and psychosocial stressors at diagnosis and during flares (with referral to mental health professionals when appropriate), and encouraging regular physical activity as tolerated. Patients using dietary approaches for treatment of their IBD should be encouraged to adopt diets that are best supported by evidence and involve monitoring for the objective resolution of inflammation. We recommend formal assessment for obesity and nutritional deficiencies, and patients should be encouraged to maintain a normal body-mass index. A shared decision-making approach to contraception should include the consideration of IBD-related factors, and risk factors for venous thromboembolism. Long-term or frequent use of high-dose non-steroidal anti-inflammatory drugs should be avoided. For primary prevention of disease in the offspring of patients with IBD, we recommend avoiding passive exposure to tobacco, using antibiotics judiciously, and considering breastfeeding when able.

摘要

环境和生活方式因素在克罗恩病和溃疡性结肠炎的自然病程中起着重要作用。一组来自国际炎症性肠病研究组织的国际专家就一系列共识声明进行了投票,旨在为炎症性肠病(IBD)的管理提供信息。这些建议包括避免克罗恩病或溃疡性结肠炎患者进行传统的吸烟,在诊断和发作时筛查抑郁、焦虑和心理社会压力源(并在适当情况下转介给心理健康专家),并鼓励在耐受的情况下定期进行身体活动。鼓励使用饮食方法治疗 IBD 的患者采用最有证据支持的饮食,并进行监测以客观缓解炎症。我们建议对肥胖和营养缺乏症进行正式评估,鼓励患者保持正常的体重指数。在进行避孕的共同决策方法时,应考虑与 IBD 相关的因素和静脉血栓栓塞的风险因素。应避免长期或频繁使用大剂量非甾体抗炎药。对于 IBD 患者的后代进行疾病的一级预防,我们建议避免被动吸烟,合理使用抗生素,并在可能的情况下考虑母乳喂养。

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