Partners In Health- Rwanda/Inshuti Mu Buzima, Rwinkwavu, Rwanda.
Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Glob Health Sci Pract. 2022 Apr 29;10(2). doi: 10.9745/GHSP-D-21-00349. Print 2022 Apr 28.
The World Health Organization has called for the elimination of hepatitis B virus (HBV) and hepatitis C virus (HCV) as public health threats by 2030. In response to the United Nations High Commissioner for Refugees requests, Rwanda became the first country to include refugees in its national viral hepatitis prevention and management program in 2019. We used secondary data to describe the implementation of the first HBV and HCV screening program among refugees in Rwanda.
Rapid diagnostic tests were used to screen for HBV surface antigen (HBsAg) and HCV antibody (anti-HCV). We used routine data collected during the HBV and HCV mass screening campaign among Burundian refugees living in Mahama camp and program records to estimate the screening coverage, the prevalence of HBV and HCV, and the cost of the campaign.
Over 28 days in February and March 2020, 26,498 unique individuals were screened for HBV and HCV, reflecting a screening coverage of 77.9% (95% confidence interval [CI]=76.5%, 78.4%). Coverage was greater than 90% among women aged 30-64 years, but younger age groups and men were less likely to be screened. On average, 946 clients were screened per day. The prevalence of anti-HCV was 1.1% (95% CI=1.0%, 1.3%), and the prevalence of HBsAg was 3.8% (95% CI=3.6%, 4.0%). We estimate that the total cost of the campaign was US$177,336.60, reflecting a per-person-screened cost of US$6.69.
Conducting a mass screening was a feasible and effective strategy to achieve high screening coverage and identify refugees who were eligible for HBV and HCV treatment. This screening program in the Mahama refugee camp can serve as a reference for other refugee camps in Rwanda and elsewhere.
世界卫生组织呼吁到 2030 年消除乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)对公共卫生的威胁。为响应联合国难民署的要求,卢旺达于 2019 年成为第一个将难民纳入国家病毒性肝炎预防和管理规划的国家。我们使用二手数据来描述在卢旺达难民中首次实施的乙型肝炎和丙型肝炎筛查计划。
使用快速诊断检测来筛查乙型肝炎表面抗原(HBsAg)和丙型肝炎抗体(抗-HCV)。我们使用在 Mahama 难民营生活的布隆迪难民中进行的乙型肝炎和丙型肝炎大规模筛查运动期间收集的常规数据和项目记录来估计筛查覆盖率、HBV 和 HCV 的流行率以及运动的成本。
在 2020 年 2 月和 3 月的 28 天内,对 26498 名个体进行了 HBV 和 HCV 的筛查,反映了 77.9%(95%置信区间[CI]=76.5%,78.4%)的筛查覆盖率。在 30-64 岁的女性中,覆盖率超过 90%,但年龄较小的群体和男性的筛查率较低。平均每天筛查 946 名患者。抗-HCV 的流行率为 1.1%(95% CI=1.0%,1.3%),HBsAg 的流行率为 3.8%(95% CI=3.6%,4.0%)。我们估计,该运动的总成本为 177336.60 美元,反映出每人筛查的成本为 6.69 美元。
开展大规模筛查是实现高筛查覆盖率和发现有资格接受乙型肝炎和丙型肝炎治疗的难民的可行且有效的策略。Mahama 难民营的这一筛查计划可以为卢旺达和其他地区的其他难民营提供参考。