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[癌症治疗期间及之后的营养与身体活动(PA):治疗益处、病理生理学、建议及临床管理]

[Nutrition and physical activity (PA) during and after cancer treatment: Therapeutic benefits, pathophysiology, recommendations, clinical management].

作者信息

Gouez Manon, Raynard Bruno, Marijnen Philippe, Ho Hio Hen Nathalie, Fervers Béatrice

机构信息

Centre Léon-Bérard, départment prévention cancer environnement, 28, rue Laënnec, 69373 Lyon cedex 08, France; Université Claude-Bernard Lyon 1, université de Lyon, EA7424, laboratoire interuniversitaire de biologie de la motricité, 29, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex, France; Centre Léon-Bérard, unité Inserm U1296 « Radiations : défense, santé, environnement », 28, rue Laënnec, 69373 Lyon cedex 08, France.

Gustave-Roussy site DR2, service de nutrition et SSR, département interdisciplinaire d'organisation du parcours patient (DIOPP), 24, rue Albert-Thuret, 94550 Chevilly-Larue, France.

出版信息

Bull Cancer. 2022 May;109(5):516-527. doi: 10.1016/j.bulcan.2022.02.008. Epub 2022 Apr 27.

Abstract

Lifestyle behaviors, such as diet and physical activity, are factors that influence risk of numerous cancers. They are also decisive during and after cancer for the course of oncological treatment, but also in the immediate and long-term prognosis, and quality of life during and after treatment. Separately, physical activity and nutritional support can reduce the risk of sarcopenia and its consequences, and improve quality of life during treatment. Whan introduced early, such a combination, increases the prognostic benefits. In remission, particularly in overweight patients, the APA-diet combination reduces the risk of cancer relapse and improves cardiovascular performance. These programs require a precise assessment of capacities and habits of each patient, and interventions of trained professionals (certified exercise instructor, dietician trained in oncology). The funding conditions for these programs exist for cancer survivors and should be considered for oncological treatment period.

摘要

生活方式行为,如饮食和体育活动,是影响多种癌症风险的因素。它们在癌症治疗期间及之后对于肿瘤治疗进程、即时和长期预后以及治疗期间及之后的生活质量也起着决定性作用。单独来看,体育活动和营养支持可以降低肌肉减少症及其后果的风险,并改善治疗期间的生活质量。如果早期引入这种组合,则会增加预后益处。在缓解期,特别是超重患者,体育活动与特定饮食的组合可降低癌症复发风险并改善心血管功能。这些方案需要对每位患者的能力和习惯进行精确评估,并且需要训练有素的专业人员(认证运动教练、肿瘤学方面训练有素的营养师)进行干预。这些方案的资金条件适用于癌症幸存者,并且在肿瘤治疗期间也应予以考虑。

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