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系统性红斑狼疮的药物监测。

Drug monitoring in systemic lupus erythematosus.

机构信息

Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, 1830 E. Monument Street, Suite 7500, Baltimore, MD, 21205, USA.

出版信息

Curr Opin Pharmacol. 2022 Jun;64:102225. doi: 10.1016/j.coph.2022.102225. Epub 2022 Apr 28.

Abstract

Therapeutic drug monitoring (TDM) is not yet accepted by systemic lupus erythematosus (SLE) treatment guidelines. Studies in SLE, however, have proven benefit in three areas: identification of non-adherence or poor adherence; targets for clinical benefit; and ranges of toxicity. This review covers the data on three medications commonly used for SLE, drawing on studies from both the SLE and non-SLE literature.

摘要

治疗药物监测(TDM)尚未被系统性红斑狼疮(SLE)治疗指南所接受。然而,SLE 领域的研究已经证明了在三个方面的益处:识别不依从或依从性差;临床获益的目标;以及毒性范围。这篇综述涵盖了三种常用于 SLE 的药物的数据,借鉴了 SLE 和非 SLE 文献中的研究。

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