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乳腺癌转移至多个器官的延迟和同步复发。

Delayed and Synchronous Recurrence of Breast Cancer Metastases in Multiple Organs.

机构信息

Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan.

Division of Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Japan.

出版信息

Intern Med. 2022 Nov 15;61(22):3355-3359. doi: 10.2169/internalmedicine.8728-21. Epub 2022 Apr 30.

DOI:10.2169/internalmedicine.8728-21
PMID:35491129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9751714/
Abstract

The most common sites of breast cancer metastasis include the lymph nodes, bones, lungs, liver, and brain. Gastrointestinal tract metastasis is rarely seen, and hypopharyngeal metastasis is extremely rare. We herein report a case of late distant recurrence of breast cancer and synchronous metastasis to the hypopharynx, stomach, ileum, bones, and lymph nodes almost 24 years after surgery. To our knowledge, this is the first case of synchronous metastasis to the hypopharynx, gastrointestinal tract, and other organs, especially after a long interval following primary mastectomy.

摘要

乳腺癌转移最常见的部位包括淋巴结、骨骼、肺、肝和脑。胃肠道转移很少见，下咽转移则极为罕见。我们在此报告一例乳腺癌术后近 24 年出现远处复发，并同时转移至下咽、胃、回肠、骨骼和淋巴结的病例。据我们所知，这是首例下咽、胃肠道及其他器官同步转移的病例，尤其是在原发乳房切除术后很长时间间隔后发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/78a9bc23585f/1349-7235-61-3355-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/52ebf7af3641/1349-7235-61-3355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/914f41daed41/1349-7235-61-3355-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/32aee6d74c3d/1349-7235-61-3355-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/78a9bc23585f/1349-7235-61-3355-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/52ebf7af3641/1349-7235-61-3355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/914f41daed41/1349-7235-61-3355-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/32aee6d74c3d/1349-7235-61-3355-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f1/9751714/78a9bc23585f/1349-7235-61-3355-g004.jpg

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本文引用的文献

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Gastric metastasis before diagnosis of primary invasive lobular breast carcinoma: a rare case presentation from Pakistan.胃转移前诊断为原发性浸润性小叶乳腺癌：来自巴基斯坦的罕见病例报告。
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Colorectal and gastric metastases from lobular breast cancer that resembled superficial neoplastic lesions.从乳腺小叶癌转移而来的结直肠和胃转移瘤，类似于表浅肿瘤病变。
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IV 期乳腺癌不同转移部位患者的临床病理特征和生存结局。
BMC Cancer. 2019 Nov 12;19(1):1091. doi: 10.1186/s12885-019-6311-z.
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Late recurrence of breast carcinoma metastasis to the hypopharynx: a case report.乳腺癌转移至下咽的晚期复发：一例报告
Springerplus. 2016 May 11;5:599. doi: 10.1186/s40064-016-2226-1. eCollection 2016.
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Annual Hazard Rates of Recurrence for Breast Cancer During 24 Years of Follow-Up: Results From the International Breast Cancer Study Group Trials I to V.24 年随访期间乳腺癌复发的年危险率：国际乳腺癌研究组试验 I 至 V 的结果。
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Evaluation of factors related to late recurrence--later than 10 years after the initial treatment--in primary breast cancer.评估原发性乳腺癌初始治疗 10 年后（即晚期复发）相关因素。
Oncology. 2013;85(2):100-10. doi: 10.1159/000353099. Epub 2013 Jul 17.
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Breast cancer metastasis to the GI tract may mimic primary gastric cancer.乳腺癌转移至胃肠道可能酷似原发性胃癌。
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Breast Cancer Res. 2007;9(3):208. doi: 10.1186/bcr1677.
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