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血清素的晶体结构。

Crystal structure of serotonin.

作者信息

Naeem Marilyn, Chadeayne Andrew R, Golen James A, Manke David R

机构信息

University of Massachusetts Dartmouth, 285 Old Westport Road, North Dartmouth, MA 02747, USA.

CaaMTech, Inc., 58 East Sunset Way, Suite 209, Issaquah, WA 98027, USA.

出版信息

Acta Crystallogr E Crystallogr Commun. 2022 Mar 10;78(Pt 4):365-368. doi: 10.1107/S2056989022002559. eCollection 2022 Apr 1.

DOI:10.1107/S2056989022002559
PMID:35492269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8983975/
Abstract

The title compound, serotonin or 5-hy-droxy-tryptamine (5-HT) [systematic name: 3-(2-amino-eth-yl)-1-indol-5-ol], CHNO, has one mol-ecule in the asymmetric unit. The conformation of the ethyl-amino side chain is - [C-C-C-C and C-C-C-N (a = aromatic, m = methyl-ene) torsion angles = -64.2 (3) and -61.9 (2)°, respectively]. In the crystal, the mol-ecules are linked into a three-dimensional network by N-H⋯O and O-H⋯N hydrogen bonds.

摘要

标题化合物,血清素或5-羟基色胺(5-HT)[系统名称:3-(2-氨基乙基)-1-吲哚-5-醇],CHNO,在不对称单元中有一个分子。乙氨基侧链的构象为 - [C-C-C-C和C-C-C-N(a = 芳环,m = 亚甲基)扭转角分别为-64.2 (3)°和-61.9 (2)°]。在晶体中,分子通过N-H⋯O和O-H⋯N氢键连接成三维网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/786e4b91aa98/e-78-00365-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/aba8393df2aa/e-78-00365-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/a1b641bb3516/e-78-00365-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/786e4b91aa98/e-78-00365-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/aba8393df2aa/e-78-00365-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/a1b641bb3516/e-78-00365-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fc/8983975/786e4b91aa98/e-78-00365-fig3.jpg

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