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机器人辅助和电视辅助胸腔镜肺叶切除术或肺段切除术治疗肺癌的最新评估:一项系统评价和荟萃分析

Updated Evaluation of Robotic- and Video-Assisted Thoracoscopic Lobectomy or Segmentectomy for Lung Cancer: A Systematic Review and Meta-Analysis.

作者信息

Zhang Jianyong, Feng Qingbo, Huang Yanruo, Ouyang Lanwei, Luo Fengming

机构信息

Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.

Department of Liver Surgery and Liver Transplantation Centre, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Front Oncol. 2022 Apr 12;12:853530. doi: 10.3389/fonc.2022.853530. eCollection 2022.

Abstract

OBJECTIVES

Robot-assisted thoracic surgery (RATS) and video-assisted thoracic surgery (VATS) are the two principal minimally invasive surgical approaches for patients with lung cancer. This study aimed at comparing the long-term and short-term outcomes of RATS and VATS for lung cancer.

METHODS

A comprehensive search for studies that compared RATS versus VATS for lung cancer published until November 31, 2021, was conducted. Data on perioperative outcomes and oncologic outcomes were subjected to meta-analysis. PubMed, Web of Science, and EMBASE were searched based on a defined search strategy to identify eligible studies before November 2021.

RESULTS

Twenty-six studies comparing 45,733 patients (14,271 and 31,462 patients who underwent RATS and VATS, respectively) were included. The present meta-analysis showed that there were no significant differences in operative time, any complications, tumor size, chest drain duration, R0 resection rate, lymph station, 5-year overall survival, and recurrence rate. However, compared with the VATS group, the RATS group had less blood loss, a lower conversion rate to open, a shorter length of hospital stay, more lymph node dissection, and better 5-year disease-free survival.

CONCLUSIONS

RATS is a safe and feasible alternative to VATS for patients with lung cancer.

摘要

目的

机器人辅助胸外科手术(RATS)和电视辅助胸外科手术(VATS)是肺癌患者的两种主要微创手术方法。本研究旨在比较RATS和VATS治疗肺癌的长期和短期结果。

方法

对截至2021年11月31日发表的比较RATS与VATS治疗肺癌的研究进行全面检索。对围手术期结果和肿瘤学结果的数据进行荟萃分析。根据既定的检索策略对PubMed、科学网和EMBASE进行检索,以识别2021年11月之前的合格研究。

结果

纳入了26项研究,共45733例患者(分别有14271例和31462例患者接受了RATS和VATS)。目前的荟萃分析表明,手术时间、任何并发症、肿瘤大小、胸腔引流持续时间、R0切除率、淋巴结站、5年总生存率和复发率方面均无显著差异。然而,与VATS组相比,RATS组失血量更少、转为开放手术的比例更低、住院时间更短、淋巴结清扫更多,且5年无病生存率更高。

结论

对于肺癌患者,RATS是VATS的一种安全可行的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ce/9039645/db98cd09afd9/fonc-12-853530-g001.jpg

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