Goos H J, de Leeuw R, Cook H, van Oordt P G
Gen Comp Endocrinol. 1986 Oct;64(1):80-4. doi: 10.1016/0016-6480(86)90031-6.
The effect of exogenous testosterone on the synthesis and release of a bioactive gonadotropic hormone-releasing hormone (GnRH)-like substance has been studied in juvenile male rainbow trout. Long-term testosterone treatment caused an increased gonadotropic hormone (GTH) release and precocious sexual maturity. Tel- and diencephalon extracts from long-term testosterone-treated juvenile rainbow trout showed significantly higher GTH-releasing activity than extracts from control animals when injected in short-term testosterone-pretreated juvenile rainbow trout. It was concluded that long-term testosterone treatment caused an increased synthesis and release of GnRH-like material.
在幼年雄性虹鳟鱼中研究了外源性睾酮对生物活性促性腺激素释放激素（GnRH）样物质合成和释放的影响。长期睾酮处理导致促性腺激素（GTH）释放增加和性早熟。当将长期接受睾酮处理的幼年虹鳟鱼的端脑和间脑提取物注射到短期接受睾酮预处理的幼年虹鳟鱼中时，其显示出比对照动物提取物显著更高的GTH释放活性。得出的结论是，长期睾酮处理导致GnRH样物质的合成和释放增加。
