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半关节同种异体移植治疗膝关节周围低度恶性和侵袭性骨肿瘤。

Hemijoint allografts in the treatment of low grade malignant and aggressive bone tumours about the knee.

作者信息

Alho A, Karaharju E O, Korkala O, Laasonen E

出版信息

Int Orthop. 1987;11(1):35-41. doi: 10.1007/BF00266056.

Abstract

Nine consecutive patients undergoing osteoarticular allogenic transplantation for low grade malignant or aggressively benign tumours have been followed up for between 8 to 15 years. Eight patients had functioning knees whilst 1 ended in arthrodesis. Of the functioning knees all had full extension but only 3 could flex more than 90 degrees. Seven patients had returned to work. Radiologically all the knees showed progressive deterioration. In spite of this only three knees were painful with exercise and none at rest. We conclude that hemijoint allografts represent a useful alternative to make good a bony defect after tumour resection about the knee, but that the ultimate result of such a reconstruction depends on survival of the joint surfaces.

摘要

9例因低度恶性或侵袭性良性肿瘤接受骨关节同种异体移植的患者接受了8至15年的随访。8例患者膝关节功能良好,1例最终关节融合。在功能良好的膝关节中,所有患者膝关节均能完全伸直,但只有3例患者膝关节屈曲超过90度。7例患者已重返工作岗位。影像学检查显示所有膝关节均有进行性退变。尽管如此,只有3例膝关节在运动时疼痛,休息时均无疼痛。我们得出结论,半关节同种异体移植是修复膝关节周围肿瘤切除术后骨缺损的一种有效替代方法,但这种重建的最终结果取决于关节面的存活情况。

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