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半关节同种异体移植治疗膝关节周围低度恶性和侵袭性骨肿瘤。

Hemijoint allografts in the treatment of low grade malignant and aggressive bone tumours about the knee.

作者信息

Alho A, Karaharju E O, Korkala O, Laasonen E

出版信息

Int Orthop. 1987;11(1):35-41. doi: 10.1007/BF00266056.

DOI:10.1007/BF00266056
PMID:3549587
Abstract

Nine consecutive patients undergoing osteoarticular allogenic transplantation for low grade malignant or aggressively benign tumours have been followed up for between 8 to 15 years. Eight patients had functioning knees whilst 1 ended in arthrodesis. Of the functioning knees all had full extension but only 3 could flex more than 90 degrees. Seven patients had returned to work. Radiologically all the knees showed progressive deterioration. In spite of this only three knees were painful with exercise and none at rest. We conclude that hemijoint allografts represent a useful alternative to make good a bony defect after tumour resection about the knee, but that the ultimate result of such a reconstruction depends on survival of the joint surfaces.

摘要

9例因低度恶性或侵袭性良性肿瘤接受骨关节同种异体移植的患者接受了8至15年的随访。8例患者膝关节功能良好,1例最终关节融合。在功能良好的膝关节中,所有患者膝关节均能完全伸直,但只有3例患者膝关节屈曲超过90度。7例患者已重返工作岗位。影像学检查显示所有膝关节均有进行性退变。尽管如此,只有3例膝关节在运动时疼痛,休息时均无疼痛。我们得出结论,半关节同种异体移植是修复膝关节周围肿瘤切除术后骨缺损的一种有效替代方法,但这种重建的最终结果取决于关节面的存活情况。

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引用本文的文献

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Osteoarticular reconstructive surgery in malignant bone tumors: the importance of external fixators.恶性骨肿瘤的骨关节重建手术:外固定器的重要性。
J Med Life. 2008 Jul-Sep;1(3):295-306.

本文引用的文献

1
Histological changes in clinical half-joint allograft replacements.临床半关节同种异体移植置换的组织学变化。
Acta Orthop Scand. 1982 Apr;53(2):295-9. doi: 10.3109/17453678208992219.
2
Osteoarticular and intercalary allograft transplantation in the management of malignant tumors of bone.
Cancer. 1982 Aug 15;50(4):613-30. doi: 10.1002/1097-0142(19820815)50:4<613::aid-cncr2820500402>3.0.co;2-l.
3
Autogenous cortical bone grafts in the reconstruction of segmental skeletal defects.自体皮质骨移植用于节段性骨缺损的重建。
J Bone Joint Surg Am. 1980 Oct;62(7):1039-58.
4
Possibilities and limitations of limb-preserving therapy for bone tumors today.当今骨肿瘤保肢治疗的可能性与局限性。
J Cancer Res Clin Oncol. 1983;106 Suppl(Suppl 1):68-76. doi: 10.1007/BF00625055.
5
Limb salvage procedure for neoplasms about the knee by spherocentric total knee arthroplasty and autogenous autoclaved bone grafting.
Clin Orthop Relat Res. 1983 Dec(181):137-45.
6
Resection alloplasty in the treatment of certain malignant bone tumors.切除性同种异体骨移植术治疗某些恶性骨肿瘤
Cancer. 1983 Dec 1;52(11):2180-4. doi: 10.1002/1097-0142(19831201)52:11<2180::aid-cncr2820521134>3.0.co;2-5.
7
Allograft replacement of all or part of the end of a long bone following excision of a tumor.肿瘤切除后对长骨末端全部或部分进行同种异体移植置换。
J Bone Joint Surg Am. 1973 Jan;55(1):1-22.
8
Half-joint allograft transplantation in human bone tumours.人骨肿瘤的半关节同种异体移植
Int Orthop. 1985;9(2):77-87. doi: 10.1007/BF00266947.
9
Use of allogenous articular bone implants as substitutes for autotransplants in adult patients.在成年患者中使用同种异体关节骨植入物替代自体移植。
Clin Orthop Relat Res. 1976 Jan-Feb(114):192-202.
10
Allogeneic transplantation in low-grade malignant bone tumours. A new operative technique to avoid amputation.低度恶性骨肿瘤的同种异体移植。一种避免截肢的新手术技术。
Acta Orthop Scand. 1979 Apr;50(2):129-38. doi: 10.3109/17453677908989747.