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Cell Rep Methods. 2022 Apr 25;2(4):100206. doi: 10.1016/j.crmeth.2022.100206.
Vesicle exo- and endocytosis mediate important biological functions, including synaptic transmission. In this issue of , Seong J. An et al. found that the fluorescently tagged C2 domain of phospholipase A binds to membrane phosphatidylcholine and thus labels vesicle membrane, allowing for super-resolution and electron microscopic visualization of vesicle trafficking.
囊泡的外排和内吞作用介导着重要的生物学功能，包括突触传递。在这一期的《自然—通讯》中，Seong J. An 等人发现，荧光标记的磷脂酶 A 的 C2 结构域与膜磷脂酰胆碱结合，从而标记囊泡膜，使得囊泡运输的超分辨率和电子显微镜可视化成为可能。
