Al-Enezi Mariam Y, John Elizabeth, Ibrahim Yehia A, Al-Awadi Nouria A
Department of Chemistry, Kuwait University P. O. Box 5969, Safat 13060 Kuwait
RSC Adv. 2021 Nov 24;11(60):37866-37876. doi: 10.1039/d1ra07428h. eCollection 2021 Nov 23.
Three novel phosphine-free Ru-alkylidenes (7a-7c) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Spectroscopic data, NMR and HRMS, along with single crystal X-ray diffraction analysis, were used to confirm their chemical structures. The tosylated carbenoid 7b showed the highest efficiency in cyclizing different acyclic diene substrates. RCM of various (un)substituted ,-diallylaniline derivatives and stereoselective RCM of different macromolecular dienes were well tolerated using only a catalytic amount (0.5-2.0 mol%) of the additive catalyst (7b) as compared to the well-known Grubbs (II) and Hoveyda-Grubbs (II) catalysts.
已合成了三种新型无膦钌亚烷基化合物（7a - 7c），并将其用作闭环复分解（RCM）反应的高效催化剂。利用光谱数据、核磁共振（NMR）和高分辨质谱（HRMS）以及单晶X射线衍射分析来确认它们的化学结构。对甲苯磺酰化类卡宾7b在环化不同的非环状二烯底物时表现出最高的效率。与著名的格拉布（II）催化剂和霍维达 - 格拉布（II）催化剂相比，仅使用催化量（0.5 - 2.0 mol%）的添加剂催化剂（7b），各种（未）取代的α,ω - 二烯丙基苯胺衍生物的RCM反应以及不同大分子二烯的立体选择性RCM反应都能很好地进行。
