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小儿肠假性梗阻:进展与挑战

Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges.

作者信息

Turcotte Marie-Catherine, Faure Christophe

机构信息

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Sainte-Justine University Health Centre, Université de Montréal, Montreal, QC, Canada.

出版信息

Front Pediatr. 2022 Apr 13;10:837462. doi: 10.3389/fped.2022.837462. eCollection 2022.

Abstract

BACKGROUND

Chronic intestinal pseudo-obstruction is a rare disorder and represents the most severe form of gastrointestinal dysmotility with significant morbidity and mortality. Emerging research shows considerable differences between the adult and pediatric population with intestinal pseudo-obstruction and the term Pediatric Intestinal Pseudo-Obstruction (PIPO) was recently proposed.

PURPOSE

The aim of this article is to provide pediatric gastroenterologists and pediatricians with an up to date review of the etiology and underlining pathophysiology, clinical features, diagnostic and management approaches currently available for PIPO and to discuss future perspectives for the diagnosis and management of this rare disease.

摘要

背景

慢性肠道假性梗阻是一种罕见疾病,是胃肠动力障碍最严重的形式,具有较高的发病率和死亡率。新出现的研究表明,成人和儿童肠道假性梗阻患者之间存在显著差异,最近提出了“小儿肠道假性梗阻(PIPO)”这一术语。

目的

本文旨在为儿科胃肠病学家和儿科医生提供关于PIPO病因、潜在病理生理学、临床特征、当前可用的诊断和管理方法的最新综述,并讨论这种罕见疾病诊断和管理的未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d30/9045367/d6fc4b06bd9d/fped-10-837462-g001.jpg

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