Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Xi'an, 710061, Shaanxi, People's Republic of China.
National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Xi'an, 710061, Shaanxi, People's Republic of China.
Surg Endosc. 2022 Nov;36(11):8170-8177. doi: 10.1007/s00464-022-09257-z. Epub 2022 May 2.
Being one of the core techniques of magnetic surgery, magnetic compression technique (MCT) has been used for digestive tract anastomosis reconstruction in experimental studies. This study verified the feasibility of gastroenteric anastomosis through natural orifice using MCT in rats.
The parent and daughter magnets were designed and manufactured for oral and anal insertion in 20 Sprague-Dawley rats. After anesthesia, the parent magnet was inserted into the colon spleen area through the anus, and the daughter magnet was inserted into the stomach through the mouth. Then the two magnets were positioned to attract each other and bind together. The position of the two magnets was monitored using X-ray. The time required for the formation of the anastomosis and expulsion of the magnets were recorded. 2 weeks later, the animal was sacrificed and the anastomotic specimen was obtained which was observed under naked eye and microscope.
The gastroenteric anastomosis was successfully performed via natural orifices in 18 out of 20 rats. The mean time to construct the anastomosis was 3.78 ± 0.88 min. X-ray examination showed that the magnets were in the appropriate position in 17 rats. The magnets were excreted in 9.47 ± 1.62 days after surgery. The gross and microscopic examination of the specimen showed that the anastomoses were patent and the mucosa at the anastomotic was smooth. The mean bursting pressure of the anastomosis was 136.94 ± 6.79 mmHg.
It is feasible to perform gastroenteric anastomosis through natural orifices by MCT.
磁压迫技术（MCT）作为磁外科的核心技术之一，已被应用于实验研究中的消化道吻合重建。本研究旨在验证 MCT 通过自然腔道进行胃肠吻合的可行性。
设计并制作了子母磁铁，以便经肛门和口腔插入大鼠体内。麻醉后，将母磁铁经肛门插入大鼠结肠脾区，将子磁铁经口插入大鼠胃部，然后调整子母磁铁的位置使它们相互吸引并结合在一起。通过 X 射线监测磁铁的位置。记录吻合形成和磁铁排出所需的时间。2 周后处死动物，获取吻合标本，肉眼和显微镜下观察。
20 只大鼠中有 18 只通过自然腔道成功完成了胃肠吻合。构建吻合的平均时间为 3.78±0.88 min。17 只大鼠 X 射线检查显示磁铁位置合适。术后 9.47±1.62 天，磁铁排出。标本的大体和显微镜检查显示吻合通畅，吻合口黏膜光滑。吻合口的平均爆破压为 136.94±6.79 mmHg。
MCT 经自然腔道进行胃肠吻合是可行的。
