Al-Harbi Mohammad Y, Albunyan Abdulhameed, Alnahari Ahmed, Kao Kalvin, Brandner Laura, El Jammal Manal, Dunn Timothy C
Therapeutic Services Deputyship, Ministry of Health, Riyadh, Kingdom of Saudi Arabia.
Ministry of Health, Riyadh, Kingdom of Saudi Arabia.
Diabetol Metab Syndr. 2022 May 3;14(1):66. doi: 10.1186/s13098-022-00831-y.
This real-world data study analyzed glucose metrics from FreeStyle Libre flash glucose monitoring in relation to scanning frequency, time in range (TIR) and estimated A1c (eA1c) in Saudi Arabia.
Anonymized reader data were analyzed according to scanning frequency quartiles, eA1c categories (<7%,≥7%‒≤9% or>9%) and TIR categories (<50%,≥50%‒≤70% or>70%). Sensors, grouped by reader, were required to have≥120 h of operation. Differences in scanning frequency, eA1c, TIR, time in hypoglycemia and hyperglycemia, and glucose variability (standard deviation [SD] and coefficient of variation [CV]) were analyzed between groups.
6097 readers, 35,747 sensors, and 40 million automatic glucose measurements were analyzed. Patients in the highest scanning frequency quartile (Q4, mean 32.0 scans/day) had lower eA1c (8.47%), greater TIR (46.4%) and lower glucose variation (SD 75.0 mg/dL, CV 38.2%) compared to the lowest quartile (Q1, mean 5.2 scans/day; eA1c 9.77%, TIR 32.8%, SD 94.9 mg/dL, CV 41.3%). Lower eA1c and higher TIR were associated with greater scanning frequency, lower glucose variability and less time in hyperglycemia.
Higher scanning frequency in flash glucose users from Saudi Arabia is associated with lower eA1c, higher TIR, lower glucose variability and less time in hypoglycemia or hyperglycemia.
这项真实世界数据研究分析了沙特阿拉伯使用FreeStyle Libre闪光葡萄糖监测仪测得的葡萄糖指标与扫描频率、血糖达标时间（TIR）和估计糖化血红蛋白（eA1c）之间的关系。
根据扫描频率四分位数、eA1c类别（<7%、≥7%‒≤9%或>9%）和TIR类别（<50%、≥50%‒≤70%或>70%）对匿名的读者数据进行分析。按读者分组的传感器需有≥120小时的运行时间。分析了各组之间在扫描频率、eA1c、TIR、低血糖和高血糖时间以及葡萄糖变异性（标准差[SD]和变异系数[CV]）方面的差异。
分析了6097名读者、35747个传感器以及4000万次自动葡萄糖测量值。与最低四分位数组（Q1，平均每天5.2次扫描；eA1c 9.77%，TIR 32.8%，SD 94.9mg/dL，CV 41.3%）相比，最高扫描频率四分位数组（Q4，平均每天32.0次扫描）的患者eA1c较低（8.47%），TIR较高（46.4%），葡萄糖变异性较低（SD 75.0mg/dL，CV 38.2%）。较低的eA1c和较高的TIR与更高的扫描频率、更低的葡萄糖变异性以及更短的高血糖时间相关。
沙特阿拉伯闪光葡萄糖监测仪使用者更高的扫描频率与更低的eA1c、更高的TIR、更低的葡萄糖变异性以及更短的低血糖或高血糖时间相关。
