Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Postgrad Med. 2022 Jun;134(5):480-486. doi: 10.1080/00325481.2022.2067612. Epub 2022 May 3.
Trigeminal neuralgia (TN) is a severe facial pain disorder that often requires surgical treatment. Neurovascular compression (NVC) has been widely accepted as the primary cause of classical TN (cTN). Vascular compression involving the near half of the cisternal segment of trigeminal nerve was the most likely cause of patient's symptoms. And severe NVC was a strong imaging predictor of an optimal surgical outcome. Operative treatments for cTN include microvascular decompression (MVD) and various ablative procedures. However, a significant proportion of cTN patients with significant NVC fail to achieve long-term pain relief after technically successful surgery. Neuroimaging using magnetic resonance imaging (MRI) provides a noninvasive method to generate objective biomarkers of eventual response to TN surgery. This paper reviewed the progress of research on the prediction of surgical outcomes in TN with MRI.
三叉神经痛（TN）是一种严重的面部疼痛疾病，通常需要手术治疗。神经血管压迫（NVC）已被广泛认为是经典三叉神经痛（cTN）的主要原因。涉及三叉神经池段近半的血管压迫是患者症状的最可能原因。严重的 NVC 是手术结果良好的强有力的影像学预测因素。cTN 的手术治疗包括微血管减压术（MVD）和各种消融术。然而，相当一部分有明显 NVC 的 cTN 患者在技术上成功的手术后无法获得长期的疼痛缓解。磁共振成像（MRI）的神经影像学提供了一种非侵入性的方法来生成对 TN 手术反应的客观生物标志物。本文综述了 MRI 预测 TN 手术结果的研究进展。
