中国首例冻存卵巢组织移植后活产以防 premature ovarian insufficiency。
First live birth in China after cryopreserved ovarian tissue transplantation to prevent premature ovarian insufficiency.
机构信息
Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China.
Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China.
出版信息
Climacteric. 2022 Aug;25(4):421-424. doi: 10.1080/13697137.2022.2064215. Epub 2022 May 3.
OBJECTIVE
This article reports the first live birth after cryopreserved ovarian tissue transplantation to prevent premature ovarian insufficiency in China.
METHODS
A patient with myelodysplastic syndrome received ovarian tissue cryopreservation before hematopoietic stem cell transplantation, and six ovarian cortex strips were thawed and transplanted into her peritoneal pocket 2 years later.
RESULTS
Pregnancy occurred spontaneously 27 months after grafting, and a healthy girl was born at 38 weeks gestation. Until now, the child has developed normally without any major diseases.
CONCLUSIONS
We report the first live birth resulting from ovarian tissue cryopreservation and transplantation in China.
目的
本文报道了首例在中国通过冻存卵巢组织移植来预防卵巢早衰的活产婴儿。
方法
一位骨髓增生异常综合征患者在进行造血干细胞移植前接受了卵巢组织冻存，2 年后将 6 条卵巢皮质条解冻并移植到其腹腔袋中。
结果
移植后 27 个月自然妊娠，38 周时分娩一健康女婴。迄今为止，该婴儿生长发育正常，无重大疾病。
结论
我们报道了首例在中国通过冻存卵巢组织移植获得的活产婴儿。
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