Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX 77030, United States; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, United States.
Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX 77030, United States; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, United States; Memorial Hermann Hospital, Texas Medical Center, Houston, TX 77030, United States.
Neuroimage. 2022 Aug 1;256:119262. doi: 10.1016/j.neuroimage.2022.119262. Epub 2022 Apr 30.
Visual inputs to early visual cortex integrate with semantic, linguistic and memory inputs in higher visual cortex, in a manner that is rapid and accurate, and enables complex computations such as face recognition and word reading. This implies the existence of fundamental organizational principles that enable such efficiency. To elaborate on this, we performed intracranial recordings in 82 individuals while they performed tasks of varying visual and cognitive complexity. We discovered that visual inputs induce highly organized posterior-to-anterior propagating patterns of phase modulation across the ventral occipitotemporal cortex. At individual electrodes there was a stereotyped temporal pattern of phase progression following both stimulus onset and offset, consistent across trials and tasks. The phase of low frequency activity in anterior regions was predicted by the prior phase in posterior cortical regions. This spatiotemporal propagation of phase likely serves as a feed-forward organizational influence enabling the integration of information across the ventral visual stream. This phase modulation manifests as the early components of the event related potential; one of the most commonly used measures in human electrophysiology. These findings illuminate fundamental organizational principles of the higher order visual system that enable the rapid recognition and characterization of a variety of inputs.
视觉输入到早期视觉皮层与语义、语言和记忆输入在高级视觉皮层中进行整合，这种整合方式快速而准确，能够进行复杂的计算，如人脸识别和单词阅读。这意味着存在使这种效率成为可能的基本组织原则。为了详细说明这一点，我们在 82 名个体进行不同视觉和认知复杂性任务时进行了颅内记录。我们发现，视觉输入在腹侧枕颞叶皮层中诱导出高度组织化的从后向前传播的相位调制模式。在单个电极上，刺激开始和结束后都有一个与试验和任务一致的、有节奏的相位进展的时间模式。前区低频活动的相位由后皮质区的先前相位预测。这种时空相位传播可能作为一种前馈组织影响，使腹侧视觉流中的信息整合成为可能。这种相位调制表现为事件相关电位的早期成分；这是人类电生理学中最常用的测量方法之一。这些发现阐明了高级视觉系统的基本组织原则，这些原则使快速识别和描述各种输入成为可能。
