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英国国家医疗服务体系数字糖尿病预防计划的参与和影响:观察性研究。

Uptake and impact of the English National Health Service digital diabetes prevention programme: observational study.

机构信息

Research Department of Primary Care and Population Health, University College London, London, UK

NHS England and Improvement, London, UK.

出版信息

BMJ Open Diabetes Res Care. 2022 May;10(3). doi: 10.1136/bmjdrc-2021-002736.

Abstract

INTRODUCTION

'Healthier You', the National Health Service (NHS) diabetes prevention programme (DPP) offers adults in England at high risk of type 2 diabetes (T2DM) an evidence-based behavioral intervention to prevent or delay T2DM onset. This study assesses the impact of a pilot digital stream of the DPP (DDPP) on glycated hemoglobin (HbA1c) and weight.

RESEARCH DESIGN AND METHODS

A service evaluation employing prospectively collected data in a prospective cohort design in nine NHS local pilot areas across England. Participants were adults with non-diabetic hyperglycemia (NDH) (HbA1c 42-47 mmol/mol or fasting plasma glucose 5.5-6.9 mmol/L) in the 12 months prior to referral. The DDPP comprised five digital health interventions (DHI). Joint primary outcomes were changes in HbA1c and weight between baseline and 12 months. HbA1c and weight readings were recorded at referral (baseline) by general practices, and then at 12-month postregistration. Demographic data and service variables were collected from the DHI providers.

RESULTS

3623 participants with NDH registered for the DDPP and of these, 2734 (75%) were eligible for inclusion in the analyses. Final (12-month) follow-up data for HbA1c were available for 1799 (50%) and for weight 1817 (50%) of registered participants. Mean change at 12 months was -3.1 (-3.4 to -2.8) kg, p<0.001 for weight and -1.6 (-1.8 to -1.4) mmol/mol, p<0.001 for HbA1c. Access to peer support and a website and telephone service was associated with significantly greater reductions in HbA1c and weight.

CONCLUSIONS

Participation in the DDPP was associated with clinically significant reductions in weight and HbA1c. Digital diabetes prevention can be an effective and wide-reaching component of a population-based approach to addressing type 2 diabetes prevention.

摘要

简介

英国国民保健制度(NHS)的糖尿病预防计划(DPP)“更健康的你”为有 2 型糖尿病(T2DM)风险的英格兰成年人提供了基于证据的行为干预措施,以预防或延缓 T2DM 的发生。本研究评估了 DPP 的数字流(DDPP)对糖化血红蛋白(HbA1c)和体重的影响。

研究设计和方法

采用前瞻性队列设计,在英格兰 9 个 NHS 试点地区进行前瞻性收集数据的服务评估。参与者为在转诊前 12 个月内患有非糖尿病性高血糖(NDH)的成年人(HbA1c 42-47mmol/mol 或空腹血糖 5.5-6.9mmol/L)。DDPP 包括五个数字健康干预措施(DHI)。联合主要结局是基线至 12 个月时 HbA1c 和体重的变化。HbA1c 和体重读数由全科医生在转诊(基线)时记录,然后在注册后 12 个月时记录。从 DHI 提供者处收集人口统计学数据和服务变量。

结果

3623 名患有 NDH 的参与者注册了 DDPP,其中 2734 名(75%)符合纳入分析的条件。1799 名(50%)注册参与者的 HbA1c 最终(12 个月)随访数据和 1817 名(50%)的体重数据可用。12 个月时的平均变化为-3.1(-3.4 至-2.8)kg,p<0.001,HbA1c 为-1.6(-1.8 至-1.4)mmol/mol,p<0.001。获得同伴支持以及网站和电话服务与 HbA1c 和体重的显著降低相关。

结论

参与 DDPP 与体重和 HbA1c 的显著降低相关。数字糖尿病预防可以成为基于人群的 2 型糖尿病预防方法的有效且广泛的组成部分。

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