Sanyaolu Adekunle, Marinkovic Aleksandra, Abbasi Abu Fahad, Prakash Stephanie, Patidar Risha, Desai Priyank, Williams Martina, Jan Abdul, Hamdy Kareem, Solomon Rachael, Balendra Vyshnavy, Ansari Maaz, Shazley Omar, Khan Nasar, Annan Rochelle, Dixon Yashika, Okorie Chuku, Antonio Afolabi
Department of Public Health, Federal Ministry of Health, Abuja, Nigeria, Abuja 0000, FCT, Nigeria.
Department of Basic Medical Science, Saint James School of Medicine, The Quarter 2640 0000, Anguilla.
World J Virol. 2023 Mar 25;12(2):109-121. doi: 10.5501/wjv.v12.i2.109.
There have been numerous concerns about the disease and how it affects the human body since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began in December 2019. The impact of SARS-CoV-2 on the liver is being carefully investigated due to an increase in individuals with hepatitis and other liver illnesses, such as alcoholic liver disease. Additionally, the liver is involved in the metabolism of numerous drugs used to treat comorbidities and coronavirus disease 2019 (COVID-19). Determining how SARS-CoV-2 affects the liver and what factors place individuals with COVID-19 at a higher risk of developing liver problems are the two main objectives of this study. This evaluation of the literature included research from three major scientific databases. To provide an update on the current impact of COVID-19 on the liver, data was collected and relevant information was incorporated into the review. With more knowledge about the effect of the disease on the liver, better management and therapeutics can be developed, and education can ultimately save lives and reduce the long-term impact of the pandemic on our population.
自2019年12月严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行开始以来，人们对这种疾病及其对人体的影响一直极为关注。由于患有肝炎和其他肝脏疾病（如酒精性肝病）的人数增加，SARS-CoV-2对肝脏的影响正在受到仔细研究。此外，肝脏参与了用于治疗合并症和2019冠状病毒病（COVID-19）的多种药物的代谢。确定SARS-CoV-2如何影响肝脏以及哪些因素使COVID-19患者发生肝脏问题的风险更高是本研究的两个主要目标。对文献的评估包括来自三个主要科学数据库的研究。为了提供关于COVID-19目前对肝脏影响的最新情况，收集了数据并将相关信息纳入综述。随着对该疾病对肝脏影响的更多了解，可以开发出更好的管理方法和治疗手段，而相关知识最终可以挽救生命并减少大流行对我们人群的长期影响。
