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PET-MPs 对果蝇寿命的性别特异性影响。

Sex-specific effects of PET-MPs on Drosophila lifespan.

机构信息

College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, Zhejiang, China.

出版信息

Arch Insect Biochem Physiol. 2022 Jul;110(3):e21909. doi: 10.1002/arch.21909. Epub 2022 May 4.

DOI:10.1002/arch.21909
PMID:35506545
Abstract

In recent years, as an emerging pollutant, microplastic (MPs) pollution is gradually becoming a research hotspot. MPs are ubiquitous in the entire ecological environment. Organisms can be exposed to MPs via inhalation or ingestion. In view of the widespread of MPs pollution, the impact of MPs on biology should be further investigated. In previous experiments, we have conducted research on the physiology of Drosophila exposed to polyethylene terephthalate microplastics (PET-MPs). However, will the lifespan of Drosophila be affected under long-term PET-MPs exposure? The analysis of variance analysis of our experimental results indicates that there are significant differences between males and females, F(1, 895) = 68.19, p < 0.001, between PET-MPs concentration, F(3, 895) = 8.11, p < 0.001. There are also significant interactions between sex and MP concentration, F(3, 895) = 4.00, p < 0.01. For Cox and log-rank test, 1 g/L of PET-MPs prolongs the lifespan of male flies. The reason for this phenomenon may be the hormesis effect.

摘要

近年来,作为一种新兴污染物,微塑料(MPs)污染逐渐成为研究热点。MPs 在整个生态环境中无处不在。生物体可以通过吸入或摄入接触到 MPs。鉴于 MPs 污染的广泛存在,应该进一步研究 MPs 对生物学的影响。在之前的实验中,我们已经研究了暴露于聚对苯二甲酸乙二醇酯微塑料(PET-MPs)的果蝇的生理学。然而,果蝇在长期 PET-MPs 暴露下寿命是否会受到影响?我们实验结果的方差分析表明,雄性和雌性之间存在显著差异,F(1, 895) = 68.19,p < 0.001,PET-MPs 浓度之间存在显著差异,F(3, 895) = 8.11,p < 0.001。性别和 MP 浓度之间也存在显著的相互作用,F(3, 895) = 4.00,p < 0.01。对于 Cox 和对数秩检验,1 g/L 的 PET-MPs 延长了雄性果蝇的寿命。这种现象的原因可能是毒物兴奋效应。

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