Rio B, Cadiou M, Andreu G, Ifrah N, Teyssandier I, Coly E, Soria J, Zittoun R
Nouv Rev Fr Hematol (1978). 1986;28(6):349-54.
Erythropoietic and granulopoietic expansion after bone marrow transplantation (BMT) are reviewed in 60 allogeneic and autologous BMT. Morphological dyserythropoiesis was more prominent than dysgranulopoiesis. Dyserythropoiesis was present with increased HbF synthesis and i antigen expression. We did not find nocturnal paroxysmal hemoglobinuria and leukocytic alkaline phosphatase level was high. CFU-GM progenitors were still reduced in number 1 year after BMT. The clusters/colonies ratio, increased at day 12 after BMT was normal by day 100. No difference between autologous and allogeneic BMT was observed.
对60例异基因和自体骨髓移植患者骨髓移植后红细胞生成和粒细胞生成的扩张情况进行了回顾。形态学红细胞生成异常比粒细胞生成异常更明显。红细胞生成异常表现为HbF合成增加和i抗原表达增加。未发现阵发性睡眠性血红蛋白尿，白细胞碱性磷酸酶水平较高。骨髓移植1年后CFU-GM祖细胞数量仍减少。集簇/集落比值在骨髓移植后第12天增加，到第100天恢复正常。自体和异基因骨髓移植之间未观察到差异。
