Williams R
Gut. 1978 Jun;19(6):578-83. doi: 10.1136/gut.19.6.578.
This paper reviews the experience gained over the past few years in two techniques of liver support, charcoal haemoperfusion and polyacrylonitrile membrane haemodialysis. Problems with charcoal haemoperfusion have centred around platelet aggregation and hypertension, and new carbon preparations with a variety of different coatings to overcome these problems are described. Haemodialysis using the PAN membrane has caused fewer side-effects and current results show that 33% of patients so treated recover consciousness. The new techniques for liver support currently being developed, including combined dialysis/perfusion systems and those based on plasma separation, are also described.
本文回顾了过去几年在两种肝脏支持技术——活性炭血液灌注和聚丙烯腈膜血液透析方面所取得的经验。活性炭血液灌注的问题主要集中在血小板聚集和高血压方面，文中还描述了为克服这些问题而采用各种不同涂层的新型碳制剂。使用聚丙烯腈膜进行血液透析产生的副作用较少，目前的结果显示，接受这种治疗的患者中有33%恢复了意识。文中还介绍了目前正在研发的新型肝脏支持技术，包括联合透析/灌注系统以及基于血浆分离的技术。
