School of Pharmacy, National Forensic Sciences University, Sector 9, Near Police Bhawan, Gandhinagar, Gujarat, India.
School of Doctoral Studies & Research (SDSR), National Forensic Sciences University, Sector 9, Near Police Bhawan, Gandhinagar, Gujarat, India.
Sci Total Environ. 2022 Aug 25;836:155622. doi: 10.1016/j.scitotenv.2022.155622. Epub 2022 May 1.
Pharmaceuticals have improved human and veterinary health tremendously over the years. But the implications of the presence of pharmaceuticals in the environment on terrestrial, avian, and aquatic organisms are still not fully comprehended. The bioaccumulation and biomagnifications of these chemicals through the food chain have long-term effects on the wildlife. The detection and quantification of such pharmaceutical residues in the environment is a tedious process and quicker methods are needed. Aptasensors are one such quick and reliable method for the identification of pharmaceutical residues in the wildlife. Aptasensors are a class of biosensors that work on the principles of biological recognition of elements. The aptamers are unique biological recognition elements with high specificity and affinity to various targets. Their efficiency makes them a very promising candidate for such sensitive research. In this review, the pharmaceutical threats to wildlife and their detection techniques using aptasensors have been discussed.
多年来，药品极大地改善了人类和兽医的健康。但是，环境中存在药品对陆地、鸟类和水生生物的影响仍未完全被理解。这些化学物质通过食物链的生物积累和生物放大对野生动物有长期影响。检测和量化环境中的这些药物残留是一个繁琐的过程，需要更快的方法。适配体传感器是一种快速可靠的方法，可用于识别野生动物中的药物残留。适配体传感器是一类基于生物识别元素工作的生物传感器。适配体是具有高特异性和亲和力的独特生物识别元素，可以识别各种目标。它们的高效性使它们成为这种敏感研究的非常有前途的候选者。在这篇综述中，讨论了药物对野生动物的威胁以及使用适配体传感器检测它们的技术。
