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冷喷止痛剂在提高急诊患者经导管疼痛耐受性中的疗效。

The efficacy of vapocoolant spray for the improved tolerance of catheter pain in emergency patients.

机构信息

Department of Clinical Science and Services, The Royal Veterinary College, University of London, Hertfordshire, UK.

出版信息

J Small Anim Pract. 2022 Aug;63(8):590-596. doi: 10.1111/jsap.13504. Epub 2022 May 4.

DOI:10.1111/jsap.13504
PMID:35508699
Abstract

OBJECTIVES

This study aimed to determine if dogs and cats presenting as an emergency had improved tolerance of intravenous catheterisation following the application of vapocoolant spray when compared to a saline control.

MATERIALS AND METHODS

A randomised controlled trial of client-owned dogs and cats presenting as an emergency and requiring intravenous catheterisation was performed. Patient signalment and mentation score were recorded. All animals were restrained and had their fur clipped over the catheterisation site. They were then randomly allocated to either have a swab saturated with vapocoolant spray (treatment) or a swab saturated with saline (control) applied to the clipped area before intravenous catheterisation. The procedure was video recorded and a single blinded observer reviewed the recordings and assigned reaction scores (0 to 3) at four time points (initial restraint, limb handling, swab application and skin puncture).

RESULTS

Between October 2020 and January 2021, a total of 100 patients (79 dogs, 21 cats) were enrolled, with 50 in each group. No significant difference in species, age, breed, sex or mentation score was detected between the two groups. There was no significant difference in reaction scores between the groups at any time point with the exception of a significantly increased swab application reaction score in the treatment group compared to the control group.

CLINICAL SIGNIFICANCE

The indirect application of vapocoolant spray via a swab before catheterisation does not significantly reduce the reaction of dogs and cats to intravenous catheterisation in an emergency setting.

摘要

目的

本研究旨在确定与生理盐水对照相比,在给出现急诊需要静脉置管的犬猫应用蒸发冷却喷雾后,其对静脉置管的耐受是否有所改善。

材料和方法

对出现急诊且需要静脉置管的患宠进行一项随机对照试验。记录患者的特征和意识评分。所有动物都被约束,并在置管部位剃去毛发。然后,将它们随机分配到用蒸发冷却喷雾浸湿的拭子(治疗组)或用生理盐水浸湿的拭子(对照组)应用于剃毛区域,然后进行静脉置管。该过程被录像记录,一位单盲观察者在四个时间点(初始约束、肢体处理、拭子应用和皮肤穿刺)回顾录像并分配反应评分(0 到 3)。

结果

2020 年 10 月至 2021 年 1 月期间,共纳入 100 例患者(79 只狗,21 只猫),每组 50 例。两组间的物种、年龄、品种、性别或意识评分无显著差异。除治疗组的拭子应用反应评分明显高于对照组外,两组在任何时间点的反应评分均无显著差异。

临床意义

在紧急情况下,通过拭子间接应用蒸发冷却喷雾并不会显著降低犬猫对静脉置管的反应。

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