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婴儿严重胸段远侧和腹段缩窄的切割球囊及支架植入治疗:从胎儿诊断到青春期

Treatment of a severe distal thoracic and abdominal coarctation with cutting balloon and stent implantation in an infant: From fetal diagnosis to adolescence.

作者信息

Carbonez Karlien, Kefer Joëlle, Sluysmans Thierry, Moniotte Stephane

机构信息

Cliniques Universitaires Saint-Luc UCL Brussels Belgium.

出版信息

Health Sci Rep. 2022 Apr 25;5(3):e625. doi: 10.1002/hsr2.625. eCollection 2022 May.

DOI:10.1002/hsr2.625
PMID:35509399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9059193/
Abstract

BACKGROUND AND AIMS

Abdominal coarctations are rare. Surgical treatment is difficult and requires re-interventions to adjust the graft material to patient growth. We report effective treatment by interventional catheterization in an infant with the concern to allow adjustment for growth and prevention of vessel damage.

METHODS AND RESULTS

After the diagnosis of abdominal coarctation at 27 weeks of gestation, an infant developed hypertension (170/70 mmHg) at 3 months of age despite medical therapy. Angio CT confirmed a 2 mm diameter, 2.3-cm-long coarctation of the descending aorta. At 4 months, a dilatation was performed using a 3 mm cutting balloon and a 5 mm Opta® balloon, Cordis®. Two noncovered Palmaz® Genesis™ XD PG1910P stents were required to keep the aortic lumen open. At 15 months, an Adventa™ V12 vascular 12 × 61 mm long covered stent was implanted to exclude an aneurysm which developed between the two stents. At 3 and 9.5 years, the stents were further dilated with a high-pressure balloon to reach 11 mm aortic diameter with no residual pressure gradient, and normal blood pressure.

CONCLUSIONS

The use of cutting balloons and stent implantation is an effective way to relieve severe obstruction in middle aortic syndrome in neonates. The technical issues encountered were the need for a low profile sheath and material to avoid femoral artery damage, and the need to use stents that can be further expanded to adult size.

摘要

背景与目的

腹主动脉缩窄较为罕见。手术治疗难度大,且需要再次干预以调整移植材料适应患者生长。我们报告了一例婴儿通过介入导管治疗获得有效治疗的病例,旨在实现对生长的适应性调整并预防血管损伤。

方法与结果

在妊娠27周诊断为腹主动脉缩窄后,一名婴儿在3个月大时尽管接受了药物治疗仍出现高血压(170/70 mmHg)。血管CT证实降主动脉存在直径2 mm、长度2.3 cm的缩窄。4个月时,使用3 mm切割球囊和5 mm Cordis® Opta®球囊进行扩张。需要植入两个未覆盖的Palmaz® Genesis™ XD PG1910P支架以保持主动脉管腔通畅。15个月时,植入一个Adventa™ V12血管12×61 mm长的覆膜支架以排除两个支架之间形成的动脉瘤。在3岁和9.5岁时,使用高压球囊对支架进一步扩张,使主动脉直径达到11 mm,无残余压力梯度,血压正常。

结论

使用切割球囊和支架植入是缓解新生儿中主动脉综合征严重梗阻的有效方法。遇到的技术问题包括需要低轮廓鞘管和材料以避免股动脉损伤,以及需要使用可进一步扩张至成人尺寸的支架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/cf5a2d14faa7/HSR2-5-e625-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/6dcf37793aaf/HSR2-5-e625-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/bb8fc2d5b4a4/HSR2-5-e625-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/ce03af81a651/HSR2-5-e625-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/cf5a2d14faa7/HSR2-5-e625-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/6dcf37793aaf/HSR2-5-e625-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/bb8fc2d5b4a4/HSR2-5-e625-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/ce03af81a651/HSR2-5-e625-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bb/9059193/cf5a2d14faa7/HSR2-5-e625-g002.jpg

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