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支架血管成形术:治疗特定严重先天性主动脉缩窄婴儿的有效替代方法。

Stent angioplasty: an effective alternative in selected infants with critical native aortic coarctation.

作者信息

Al-Ata J, Arfi A M, Hussain A, Kouatly A, Galal M O

机构信息

Section of Pediatric Cardiology, Department of Cardiovascular Diseases, King Faisal Specialist Hospital & Research Center, MBC J-16, P. O. Box 40047, 21499 Jeddah, Saudi Arabia.

出版信息

Pediatr Cardiol. 2007 May-Jun;28(3):183-92. doi: 10.1007/s00246-006-0074-4. Epub 2007 Apr 24.

Abstract

Management of native aortic coarctation during early months of life poses therapeutic challenges, and there is no consensus among medical professionals regarding a management plan. Much can be argued about the benefits, limitations, and/or complications of transcatheter versus surgical intervention in such cases. Occasionally, the complexity of the lesions limits management options. Therefore, each patient requires individual management decisions because there is no one therapeutic plan that satisfies all patients. In this report, four critically ill infants who had complex native coarctation are presented. Surgical repair was not possible because of relative contraindications. The patients underwent transcatheter stent implantation (six procedures and seven stents) as a nondefinitive procedure with acceptable results. Three patients improved. One patient did not survive, mainly due to other major complications. Multiple reexpansions of the stents were carried out when indicated. After a mean follow-up of 45 months (range, 41-49), the three survivors were doing fine and had gained an average weight of 9.7 kg (range, 6.6-13.3). At the time of reporting, the relative contraindications no longer exist and the final surgical repair can be carried out. Our experience suggests that in certain situations and in critically ill infants with complex form of coarctation, stent angioplasty can be used as a life-saving palliative procedure. Further reexpansions can be done when required. This may serve as a bridge to major surgical repair in the future.

摘要

在生命的最初几个月对先天性主动脉缩窄进行管理面临着治疗挑战,医学专业人员对于管理方案尚未达成共识。在此类病例中,关于经导管介入与手术干预的益处、局限性和/或并发症存在诸多争议。偶尔,病变的复杂性会限制管理选择。因此,由于没有一种治疗方案能满足所有患者,每个患者都需要个体化的管理决策。在本报告中,介绍了4例患有复杂先天性缩窄的危重症婴儿。由于存在相对禁忌证,无法进行手术修复。这些患者接受了经导管支架植入术(6次手术,植入7个支架),作为一种非确定性手术,结果可接受。3例患者病情改善。1例患者死亡,主要是由于其他严重并发症。在有指征时对支架进行了多次再扩张。平均随访45个月(范围41 - 49个月)后,3名存活者情况良好,平均体重增加了9.7千克(范围6.6 - 13.3千克)。在报告时,相对禁忌证已不存在,可以进行最终的手术修复。我们的经验表明,在某些情况下,对于患有复杂形式缩窄的危重症婴儿,支架血管成形术可作为一种挽救生命的姑息性手术。必要时可进一步进行再扩张。这可能会成为未来进行主要手术修复的桥梁。

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