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腹腔镜下腹膜后淋巴结清扫术与开放性腹膜后淋巴结清扫术治疗睾丸癌的临床及围手术期结果比较

Laparoscopic retroperitoneal lymph node dissection versus open retroperitoneal lymph node dissection for testicular cancer: A comparison of clinical and perioperative outcomes.

作者信息

Shishido Toshihide, Okegawa Takatsugu, Hayashi Kenjiro, Masuda Kazuki, Taguchi Satoru, Nakamura Yu, Tambo Mitsuhiro, Fukuhara Hiroshi

机构信息

Department of Urology, Hachioji Medical Center, Tokyo Medical University, 1163, Tatemachi, Hachioji, Tokyo, Japan.

Department of Urology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, Japan.

出版信息

Asian J Urol. 2022 Apr;9(2):119-124. doi: 10.1016/j.ajur.2021.05.004. Epub 2021 May 25.

Abstract

OBJECTIVE

This study was performed to evaluate the clinical and perioperative outcomes of laparoscopic retroperitoneal lymph node dissection (L-RPLND) and open retroperitoneal lymph node dissection (O-RPLND) performed by one surgeon at a single center.

METHODS

We evaluated 30 patients with stage IIA germ cell tumors who underwent retroperitoneal lymph node dissection (15 underwent L-RPLND and 15 underwent O-RPLND) at our institution between April 1, 2010 and March 31, 2018. The clinical parameters were compared between patients who underwent L-RPLND using the retroperitoneal approach and those who underwent O-RPLND using the transperitoneal approach. There were no significant differences in the background characteristics of the two groups except for the median follow-up duration (46 months for L-RPLND and 71 months for O-RPLND, =0.02).

RESULTS

L-RPLND was associated with a shorter mean operative time (mean 222 min for L-RPLND 453 min for O-RPLND, <0.001). There was significantly less blood loss during surgery in the L-RPLND group compared to the O-RPLND group (mean 165 mL for L-RPLND 403 mL for O-RPLND, <0.001). Parameters related to postoperative recovery were significantly better for the L-RPLND group than for the O-RPLND group. There were no differences in the histopathological characteristics between the two groups. No patients in either group exhibited disease recurrence.

CONCLUSION

Patients who underwent L-RPLND had more rapid recovery, and shorter hospital stay compared to those who underwent O-RPLND; complications were comparable between the two groups. L-RPLND is an efficient procedure with the benefits of minimally invasive surgery.

摘要

目的

本研究旨在评估由同一外科医生在单中心进行的腹腔镜腹膜后淋巴结清扫术(L-RPLND)和开放腹膜后淋巴结清扫术(O-RPLND)的临床及围手术期结果。

方法

我们评估了2010年4月1日至2018年3月31日期间在本机构接受腹膜后淋巴结清扫术的30例IIA期生殖细胞肿瘤患者(15例行L-RPLND,15例行O-RPLND)。比较了采用腹膜后入路行L-RPLND的患者与采用经腹入路行O-RPLND的患者的临床参数。除中位随访时间外,两组的背景特征无显著差异(L-RPLND为46个月,O-RPLND为71个月,P=0.02)。

结果

L-RPLND的平均手术时间较短(L-RPLND平均为222分钟,O-RPLND为453分钟,P<0.001)。与O-RPLND组相比,L-RPLND组手术中的失血量明显更少(L-RPLND平均为165毫升,O-RPLND为403毫升,P<0.001)。L-RPLND组术后恢复相关参数明显优于O-RPLND组。两组的组织病理学特征无差异。两组均无患者出现疾病复发。

结论

与接受O-RPLND的患者相比,接受L-RPLND的患者恢复更快,住院时间更短;两组并发症相当。L-RPLND是一种具有微创手术益处的有效手术方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a41/9051357/fbafd72feadd/gr1.jpg

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