Poulakis Vassilis, Skriapas Konstantinos, de Vries Rachelle, Dillenburg Wolfgang, Ferakis Nikolaos, Witzsch Ulrich, Becht Edward
Department of Urology, Northwest Hospital, Stiftung Hospital zum Heiligen Geist, Frankfurt am Main, Germany.
Urology. 2006 Jul;68(1):154-60. doi: 10.1016/j.urology.2006.01.023. Epub 2006 Jul 3.
To compare the postoperative quality of life (QOL) and reconvalescence in patients with clinical Stage I nonseminomatous germ cell tumor (NSGCT) after laparoscopic retroperitoneal lymph node dissection (L-RPLND) and the open procedure (O-RPLND).
Twenty-one patients with NSGCT who underwent transperitoneal L-RPLND were matched and compared with 29 patients who underwent O-RPLND. The operative, QOL, and recovery data and complications and cure rates were analyzed for both groups.
The mean follow-up time for the L-RPLND and O-RPLND groups was 14 months (range 6 to 20) and 26 months (range 8 to 38), respectively. No major complication requiring open surgical revision or prolongation of hospitalization was observed intraoperatively or postoperatively in either group. However, the early and late minor postoperative complications were significantly greater in the O-RPLND group than in the L-RPLND group (P <0.001). The L-RPLND patients had a significantly shorter hospitalization, greater QOL scores, and a faster return to normal activities than did the O-RPLND patients (all P <0.001).
L-RPLND for patients with clinical Stage I NSGCT is a safe and efficacious procedure, with a faster reconvalescence and greater postoperative QOL than after O-RPLND.
比较临床I期非精原细胞瘤性生殖细胞肿瘤（NSGCT）患者行腹腔镜腹膜后淋巴结清扫术（L-RPLND）与开放手术（O-RPLND）后的术后生活质量（QOL）和康复情况。
将21例行经腹L-RPLND的NSGCT患者与29例行O-RPLND的患者进行匹配和比较。分析两组的手术、QOL、恢复数据以及并发症和治愈率。
L-RPLND组和O-RPLND组的平均随访时间分别为14个月（范围6至20个月）和26个月（范围8至38个月）。两组术中或术后均未观察到需要开放手术修正或延长住院时间的重大并发症。然而，O-RPLND组术后早期和晚期的轻微并发症明显多于L-RPLND组（P<0.001）。L-RPLND患者的住院时间明显更短，QOL评分更高，恢复正常活动的速度比O-RPLND患者更快（均P<0.001）。
对于临床I期NSGCT患者，L-RPLND是一种安全有效的手术，与O-RPLND相比，康复更快，术后QOL更高。
