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肺泡微结石症一例罕见病例。

A Rare Case of Pulmonary Alveolar Microlithiasis.

作者信息

Madhala Divya, Govindarajan Meera, Kulasekaran Rajkumar

机构信息

Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Pathology, R&D Histopathology Lab, Chennai, IND.

出版信息

Cureus. 2022 Apr 2;14(4):e23769. doi: 10.7759/cureus.23769. eCollection 2022 Apr.

DOI:10.7759/cureus.23769
PMID:35509742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9061221/
Abstract

Pulmonary alveolar microlithiasis is a rare, inherited disease affecting males usually. We present a case of a 32-year-old male who had shortness of breath for two years. The chest x-ray showed fine micronodules in a sandstorm-like pattern distributed bilaterally throughout the lungs, and a high-resolution computed tomography (HRCT) showed diffuse bilateral calcification of the lungs. Following this, a bronchoscopic biopsy was done to confirm the diagnosis.

摘要

肺泡微石症是一种罕见的遗传性疾病，通常影响男性。我们报告一例32岁男性，他有两年的气短症状。胸部X光显示双肺呈沙尘暴样分布的细小结节，高分辨率计算机断层扫描（HRCT）显示双肺弥漫性钙化。此后，进行了支气管镜活检以确诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f63/9061221/5bdedea3d61e/cureus-0014-00000023769-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f63/9061221/5bdedea3d61e/cureus-0014-00000023769-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f63/9061221/5bdedea3d61e/cureus-0014-00000023769-i01.jpg

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本文引用的文献

1
Pulmonary Alveolar Microlithiasis "Stone Lungs": A Case of Clinico-Radiological Dissociation.肺泡微石症“石肺”：一例临床与放射学分离的病例
Cureus. 2016 Aug 24;8(8):e749. doi: 10.7759/cureus.749.
2
A case of pulmonary alveolar microlithiasis associated with a homozygous 195 kb deletion encompassing the entire SLC34A2 gene.一例肺泡微石症合并纯合子195 kb缺失，该缺失涵盖整个SLC34A2基因。
Clin Case Rep. 2016 Mar 11;4(4):412-5. doi: 10.1002/ccr3.532. eCollection 2016 Apr.
3
Pulmonary alveolar microlithiasis: review of the 1022 cases reported worldwide.
肺泡微结石症：全球1022例报告综述。
Eur Respir Rev. 2015 Dec;24(138):607-20. doi: 10.1183/16000617.0036-2015.
4
Pulmonary alveolar microlithiasis: report on 576 cases published in the literature.肺泡微石症：文献中576例病例报告
Sarcoidosis Vasc Diffuse Lung Dis. 2004 Oct;21(3):173-81.
5
Pulmonary alveolar microlithiasis: a rare familial inheritance with report of six cases in a family. Contribution of six new cases to the number of case reports in Turkey.
Respiration. 2001;68(2):204-9. doi: 10.1159/000050494.